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Tumor Characteristics and Molecular Subtypes in Breast Cancer Screening with Digital Breast Tomosynthesis : The Malmö Breast Tomosynthesis Screening Trial

Background Screening accuracy can be improved with digital breast tomosynthesis (DBT). To further evaluate DBT in screening, it is important to assess the molecular subtypes of the detected cancers. Purpose To describe tumor characteristics, including molecular subtypes, of cancers detected at DBT compared with those detected at digital mammography (DM) in breast cancer screening. Materials and Me

Celebrities, air travel, and social norms

The year 2018 saw the rise of a new global youth movement, Fridays for Future. The organization underlines the importance of personal accountability for greenhouse gas emissions, specifically in the context of air travel. This position is in stark contrast to views associating aeromobility with status. Celebrities in particular maintain personal brands based on frequent flying. This paper assesses

Modeling Microgels with a Controlled Structure across the Volume Phase Transition

Thermoresponsive microgels are soft colloids that find widespread use as model systems for soft matter physics. Their complex internal architecture, made of a disordered and heterogeneous polymer network, has been so far a major challenge for computer simulations. In this work, we put forward a coarse-grained model of microgels whose structural properties are in quantitative agreement with results

Effect of hydrogen chloride etching on carrier recombination processes of indium phosphide nanowires

Introduction of in situ HCl etching to an epitaxial growth process has been shown to suppress radial growth and improve the morphology and optical properties of nanowires. In this paper, we investigate the dynamics of photo-generated charge carriers in a series of indium phosphide nanowires grown with varied HCl fluxes. Time resolved photo-induced luminescence, transient absorption and time resolv

Impact of carbon deposition on diffusion parameters in porous anodes of solid oxide fuel cells using the lattice Boltzmann method

A solid oxide fuel cell (SOFC) is an electrochemical device that converts energy of a chemical reaction into electrical and thermal energy. Besides lack of pollutants and high electrical efficiency, one of the main advantages of SOFCs is the flexibility of using a wide range of fuels, i.e., natural gas, biogas, or any reactant with hydrogen as constituent. However, the use of hydrocarbon fuels can

Empirical correlations for the performance of a PEFC considering relative humidity of fuel and oxidant gases

The growing energy demand and the impact of polluting gases lead to the necessity of alternative energy sources and conversion energy devices. Fuel cells (FCs) appears as a suitable solution for facing the mentioned issues. Predicting the behavior of a polymer electrolyte fuel cell (PEFC) under different conditions represents a proper initial step to solve the several issues, e.g., aging water bal

Rhegmatogenous Retinal Detachment in Nonsyndromic High Myopia Associated with Recessive Mutations in LRPAP1

Purpose: To describe a new form of childhood-onset rhegmatogenous retinal detachment (RRD) in autosomal recessive high myopia associated with mutations in LRPAP1. Design: Retrospective cohort study. Participants: A total of 12 children (24 eyes) with recessive LRPAP1 mutations and associated high myopia. Methods: Serial ophthalmological examination and retinal imaging during 4.6±1.9 (mean ± standa

A simple correction for the parallax effect in X-ray pair distribution function measurements

Total scattering and pair distribution function (PDF) analysis has created new insights that traditional powder diffraction methods have been unable to achieve in understanding the local structures of materials exhibiting disorder or complex nanostructures. Care must be taken in such analyses as subtle and discrete features in the PDF can easily be artefacts generated in the measurement process, w

EV powertrain topologies for electric road applications

Electric road systems (ERS) are technologies that allow to charge electric vehicles (EVs) while they are driving. A large scale implementation of ERS would allow to significantly reduce the installed battery capacity on board the vehicles, which consequently reduces their weight and cost. Due to geographical, practical and economic constraints the ERS is not expected to cover the full extension of

Influence of Leptin and Adiponectin Supplementation on Intraepithelial Lymphocyte and Microbiota Composition in Suckling Rats

Dietary components in early life play a role in both microbiota and intestinal immune system maturation in mammalian species. Adipokines, as endogenously produced hormones from breast milk, may have an impact on this process. The aim of the present study was to establish the influence of leptin and adiponectin supplementation during suckling on the intraepithelial lymphocyte composition, intestina

A Collaborative Survey of 80 Mutations in the BRCA1 Breast and Ovarian Cancer Susceptibility Gene : Implications for Presymptomatic Testing and Screening

OBJECTIVES:To report the initial experience of an international group of investigators in identifying mutations in the BRCA1 breast and ovarian cancer susceptibility gene, to assess the spectrum of such mutations in samples from patients with different family histories of cancer, and to determine the frequency of recurrent mutations.DESIGN:Nine laboratories in North America and the United Kingdom

Did the Computer Revolution shift the fortunes of U.S. cities? Technology shocks and the geography of new jobs

This paper shows how the Computer Revolution of the 1980s shifted the economic trajectories of U.S. cities. Examining the emergence of new occupational titles in official census classifications, we document a sharp reversal in the skill content of new jobs. While technological change was biased towards routine skills throughout the 1970s, new job titles mainly appeared in occupations and industrie

Industrial renewal in the 21st century: evidence from US cities

Industrial renewal in the 21st century: evidence from US cities. Regional Studies. Where and why do new industries emerge? Using revisions of official industrial classifications, this paper documents the appearance of new industries in the US economy between 2000 and 2010 stemming directly from technological advances. Examining differences in new industry creation across cities, this paper shows t

Patents and corporate credit risk

A vast literature documents a positive relationship between patents and companies stock market performance. Nevertheless, evidence on the influence of patents on companies’ debt capacity remains sparse. In this article, we examine the relationship between companies’ patent portfolios and their credit rating, providing relevant, albeit indirect, evidence on patents as a debt funding mechanism. Usin

Uber Happy? Work and Well-being in the “Gig Economy”

We study the rise of the so-called “gig economy” through the lens of Uber and its drivers in the United Kingdom. Using administrative data from Uber and a new representative survey of London drivers, we explore their backgrounds, earnings, and subjective well-being. We find that the vast majority of Uber drivers are male immigrants, primarily drawn from the bottom half of the London income distrib

Use and categorization of Light Detection and Ranging vegetation metrics in avian diversity and species distribution research

Aim: Vegetation structure is a key determinant of animal diversity and species distributions. The introduction of Light Detection and Ranging (LiDAR) has enabled the collection of massive amounts of point cloud data for quantifying habitat structure at fine resolution. Here, we review the current use of LiDAR‐derived vegetation metrics in diversity and distribution research of birds, a key group f