Diet supplemented with pancreatic-like enzymes of microbial origin restores the hippocampal neuronal plasticity and behaviour in young pigs with experimental exocrine pancreatic insufficiency
It is postulated that exocrine pancreatic insufficiency (EPI) can evoke neurological disorders. In the present study pancreatic-like enzymes of microbial origin (PLEM) were examined as a functional food component, with the goal of improving cognitive function and brain structure in a pig model of EPI. EPI in the present study induced alterations in the behaviour of the pigs as well as degenerative