Epithelial ovarian cancer (EOC) is considered to secrete various factors in order to promote peritoneal dissemination through cell-to-cell interaction between cancer and mesothelial cells. We previously revealed that TGF-β secreted from EOC induces normal human peritoneal mesothelial cells (HPMCs) to differentiate into cancer-associated mesothelial cells (CAMCs). However, the relationship between

Latin America has constituted a recent example of inclusive growth by reducing poverty and income inequality simultaneously during the latest commodity boom. Against the backdrop of non-inclusive and non-transformative nature of commodity booms, we ask whether growth of agriculture was able to speed up structural transformation, and, relatedly, if agricultural growth was inclusive. We examine 16 c

Temperature sums are widely used to predict the seasonal timing of yearly recurring biological events, such as flowering, budburst, and hatching. We use a classic energy allocation model for annual plants to compare a strategy for reproductive timing that follows a temperature sum rule (TSR) with a strategy that follows an optimal control rule (OCR) maximizing reproductive output. We show that the

In Parkinson's disease, the degeneration of dopaminergic neurons in substantia nigra leads to a decrease in the physiological levels of dopamine in striatum. The existing dopaminergic therapies effectively alleviate the symptoms, albeit they do not revert the disease progression and result in significant adverse effects. Transplanting dopaminergic neurons derived from stem cells could restore dopa

Key message: Analyses of barley mat-c loss of function mutants reveal deletions, splice-site mutations and nonsynonymous substitutions in a key gene regulating early flowering. Abstract: Optimal timing of flowering is critical for reproductive success and crop yield improvement. Several major quantitative trait loci for flowering time variation have been identified in barley. In the present study,

Förekomsten av kostrelaterade sjukdomar ökar, framför allt i grupper som lever under ekonomisk knapphet. Detta förklaras ofta med det höga priset på eller den höga prisökningstakten för hälsosamma livsmedel. De samhällsekonomiska implikationerna av en sådan förklaring är omfattande eftersom de motiverar mer omfattande omfördelning eller prismanipulation som lösning på hälsoproblemen. Detta bidrag

På samma sätt som det är naturligt för ungdomar från bruksorter att flytta till Stockholm bör Stockholmsungdomar ställa in sig på att flytta ut från stan, skriver Ingemar Bengtsson, universitetslektor i fastighetsvetenskap vid Lunds universitet.

In this chapter, a detailed review of the current understanding of thephysical processes of droplet breakup in a high-pressure homogenizer (HPH) is presented,covering breakup mechanisms by laminar shear in the gap inlet and its boundarylayers, by local turbulence in the gap exit jet, and by cavitation. Experimentalevidence of the effects of homogenization pressure, Thoma number, dispersed andcontiIn this chapter, a detailed review of the current understanding of the physical processes of droplet breakup in a high-pressure homogenizer (HPH) is presented, covering breakup mechanisms by laminar shear in the gap inlet and its boundary layers, by local turbulence in the gap exit jet, and by cavitation. Experimental evidence of the effects of homogenization pressure, Thoma number, dispersed and

Föreläsningen är en märklig undervisningsform. Samtidigt som den är den vanligast förekommandemetoden, är den också den mest föraktade. Det finns gott om högskolepedagogisklitteratur som förklarar varför föreläsningen är olämplig för att stimulera lärande. Ändåfortsätter vi föreläsa. Det kan tyckas motsägelsefullt.Denna reflektion vänder på frågan och letar efter föreläsningens fördelar. Utifrån t

Introduction: Long QT syndrome (LQTS) mutation carriers have elevated the risk of cardiac events even in the absence of QTc prolongation; however, mutation penetrance in patients with normal QTc may be reflected in abnormal T-wave shape, particularly in KCNH2 mutation carriers. We aimed to assess whether the magnitude of a three-dimensional T-wave vector (TwVM) will identify KCNH2-mutation carrier

Background: Occupational balance is fundamental to occupational therapy and occupational science. Therefore, the Occupational Balance Questionnaire (OBQ) was developed and has previously been found psychometrically valid according to classical test theory. Aim: To investigate the internal construct validity of the OBQ using Rasch measurement theory. Material and methods: Data from two general popu

In this study, effects of various geometrical parameters of a new winglet longitudinal vortex generator (LVG) on heat transfer and flow characteristics in a rectangular channel were investigated by a numerical method, and the influence of various parameters was analyzed. A comparative study of effects of elliptical pole parameters, the thickness, the length, the height, the attack angle, the trans

Background and purpose — The all-polyethylene tibial (APT) component, introduced in the early 1970s, was surpassed by metal-backed tibial (MBT) trays as the first choice for total knee arthroplasty (TKA). With improved polyethylene, the modern APT components can reduce costs, and have shown equivalent results in survivorship and early migration of the cruciate-retaining and cruciate-stabilizing de

The development of soft anisotropic building blocks is of great interest for various applications in soft matter. Furthermore, such systems would be important model systems for ordering phenomena in fundamental soft matter science. In this work, we address the challenge of creating hollow and anisotropically shaped thermoresponsive microgels, polymeric networks with a solvent filled cavity in thei

Insects visit flowers not only to forage for nectar or pollen but also to search for hosts or prey, and to look for suitable habitats for breeding sites. In oil palm flowers, it has been documented that not all flower-visiting insects are pollinators, but some insects are recognized as predators, parasitoids or saprophages, which may affect the abundance and persistence of the weevil pollinating o

Background: To assess whether a prespecified statistical model based on the four kallikrein markers measured in blood—total, free, and intact prostate-specific antigen (PSA), together with human kallikrein-related peptidase 2 (hK2)—or any individual marker measured in pretreatment serum were associated with biochemical recurrence-free (BCR) or metastasis-free survival after radical prostatectomy (

Aim: Children born preterm are at increased risk of reduced lung function. The aim was to test whether lung function was associated with pulmonary vascular resistance. Methods: Participants were recruited from a population-based cohort born in 2004-2007. Lung function was assessed with spirometry after administration of a beta2-agonist. Forced vital capacity (FVC) and forced expiratory volume in o

Background: Acute pancreatitis (AP) is a frequent disorder with considerable morbidity and mortality. Obesity has previously been reported to influence disease severity. Objective: The aim of this study was to investigate the association of adipose and muscle parameters with the severity grade of AP. Methods: In total 454 patients were recruited. The first contrast-enhanced computed tomography of