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Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype

Blood-brain barrier (BBB) dysfunction might be an important component of many neurodegenerative disorders. In this study, we investigated its role in dementia using large clinical cohorts. The cerebrospinal fluid (CSF)/plasma albumin ratio (Qalb), an indicator of BBB (and blood-CSF barrier) permeability, was measured in a total of 1015 individuals. The ratio was increased in patients with Alzheime

Extraction of lethal events from Wikipedia and a semantic repository

This paper describes the extraction of information on lethal events from the Swedish version of Wikipedia. The information searched includes the persons’ cause of death, origin, and profession. We carried out the extraction using a processing pipeline of available tools for Swedish including a part-of-speech tagger, a dependency parser, and manually-written extraction rules. We also extracted stru

Linking Entities Across Images and Text

This paper describes a set of methods to link entities across images and text. As a corpus, we used a data set of images, where each image is commented by a short caption and where the regions in the images are manually segmented and labeled with a category. We extracted the entity mentions from the captions and we computed a semantic similarity between the mentions and the region labels. We also

Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression

Background Dehydroepiandrosterone (DHEA) and its sulfated ester DHEA-sulfate (DHEA-S), (together DHEA[S]), are the most abundant adrenal steroids in humans and are found in blood and the brain, where they function as neurosteroids with direct receptor affinities. Preclinical studies suggest that DHEA(S) has antidepressant/neuroprotective properties, and exogenously administered DHEA has shown anti