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Aims Immediate treatment with a loading dose of clopidogrel at diagnosis of ST-segment elevation myocardial infarction (STEMI) is recommended by ESC/AHA/ACC guidelines in patients eligible for primary percutaneous coronary intervention (PCI). However, the evidence for this practice is scarce. Methods and results All patients who underwent PCI for STEMI in Sweden between 2003 and 2008 were identifi

Although bone marrow (BM) represents the main site for postnatal NK cell development, recently a distinct thymic-dependent NK cell pathway was identified. These studies were designed to investigate the role of cytokines in regulation of thymic NK cells and to compare with established regulatory pathways of BM-dependent NK cell compartment. The common cytokine receptor gamma-chain (Il2rg) essential

In the emerging knowledge economy, universities are adopting a key role as producers of scientific knowledge and skills, and they are experiencing far reaching changes in their tasks. Their main mission is no longer confined to education and research, but increasingly also covers technology transfer and commercialisation activities. The aim of this paper is to examine to what extent this phenomeno

The purpose of this study was to compare facial growth in patients with unilateral complete cleft lip and palate (UCLP) in whom the palate was repaired with the von Langenbeck procedure at 8 months (L-8), or the Wardill procedure at 18 months (W-18). A total of 151 unaffected subjects were used as a reference series. Sixty-one adult patients, 34 in the L-8 group and 27 in the W-18 group, were inve

Aims: This study summarises the health-related quality of life (HRQOL) scores and absenteeism caused by sinus problems in patients awaiting surgery with the diagnoses recurrent acute rhinosinusitis (RARS), chronic rhinosinusitis with nasal polyps (CRS+NP) or CRS without nasal polyps (CRS-NP), in a prospective multi-centre study. Methodology: Two hundred and seven patients with RARS, CRS+NP or CRS-

Given images of a scene taken by a moving camera or recordings of a moving smart phone playing a song by a microphone array, how hard is it to reconstruct the scene structure or the moving trajectory of the phone? In this thesis, we study and solve several fundamental geometric problems in order to provide solutions to these problems. The key underlying technique for solving such geometric probl

Alcohol intoxication causes many accidental falls presented at emergency departments, with the injury severity often related to level of blood alcohol concentration (BAC). One way to evaluate the decline in postural control and the fall risk is to assess standing stability when challenged. The study objective was to comprehensively investigate alcohol-related impairments on postural control and ad

I nöjesparkens åkattraktioner är det din egen kropp som upplever krafterna i Newtons lagar, när den accelereras i 1, 2 och 3 dimensioner. Du får uppleva det fria fallets tyngdlöshet - eller känna dig mycket tyngre än vanligt när berg- och dalbanan går igenom en dal. Åkattraktinerna ger mpnga fina exempel på krafter i idealiserade situationer, som till exempel Slänggungan/Kättingflygaren på Liseber

This thesis presents two sources of extreme ultraviolet (XUV) radiation based on high-order harmonic generation (HHG) in gases. The sources were developed for experiments requiring high-flux harmonic beams or HHG pulses at high-repetition rate. These were used experimentally to image nano-scale objects. The high-flux HHG source was used for digital in-line holography, and the high-repetition rate

Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by both neurological and systemic abnormalities. We examined the peripheral immune system and found widespread evidence of innate immune activation detectable in plasma throughout the course of HD. Interleukin 6 levels were increased in HD gene carriers with a mean of 16 years before the predicted onset of clinical

Not only the argument from contingency for the existence of God but also the theistic idea that God is the metaphysical foundation of the world seem to presuppose the intelligibility and validity of the following question: Why is there anything contingent at all? However, it has been argued that, upon closer inspection, this question is a pseudo-question: a question which presupposes illegitimate