Background and Objectives. Although anagrelide is widely used in the treatment of throm-bocythemia in myeloproliferative diseases, there is currently limited information on the efficacy and toxicity of its long-term use. This prospective study investigated clinical toxicity and efficacy of anagrelide during two years of treatment. Design and Methods. A multicenter, open, phase II study of anagreli

An increase of creatine kinase MB (CKMB) in serum has long been used as a marker for acute myocardial infarction (AMI). It is important with an early diagnosis and since the amount of the CKMB2 isoform rises above reference levels much earlier than the total creatine kinase amount, quantification of CKMB isoforms could be a feasible alternative for early analysis. The two CKMB isoforms differ by o

Popular Abstract in Swedish Avhandlingen utgörs av en kritisk edition av Johannes Annorelius? latinska brev till brodern Julius (G3, Uppsala universitetsbibliotek). I början av 1700-talet lämnade Johannes Annorelius Uppsala och blev katolik och kapucinmunk i Flandern. Från klostret skrev han många, långa brev på franska och latin till sin lutherske bror i Sverige. I breven förklarar han varför hanThis book presents a critical edition of the Latin letters in ms. G3 (Uppsala University Library) from Johannes Annorelius to his brother. Johannes Annorelius left Sweden as a young student in the beginning of the 18th century and settled down in Flanders, where he converted to the Catholic faith and became a Capuchin friar. In the Capuchin friary Annorelius wrote several extensive letters in Fren

Our main aim is to understand the phenomena coercion by regarding how it is created and maintained during coercive care of drug abusers in Sweden. In this article we follow processes through coercive care by stories from social workers and clients. 23 interviews were conducted with 13 social workers in the social services and 10 persons who have been under coercive care. The material derives from

Measurements are presented of differential dijet cross sections in diffractive photoproduction (Q(2) < 0.01 GeV2) and deep-inelastic scattering processes (DIS, 4 < Q2 < 80 GeV2). The event topology is given by ep -> eXY, in which the system X, containing at least two jets, is separated from a leading low-mass baryonic system Y by a large rapidity gap. The dijet cross sections are compared with NLO

Tissue transglutaminase (tTg) has been identified as the major autoantigen in coeliac disease (CD). ELISA methods have been developed for measuring the autoantibody. There are divergent reports on the effects of calcium on the antibody binding to tTg. Furthermore, zinc is a potent inhibitor of tTg. To better understand the role of transglutaminase in CD, we have studied the stability of commercial

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Two lesions, actinic keratosis (AK) and squamous cell carcinoma in situ (CIS), are believed to be precursors of squamous cell carcinoma (SCC) of the skin. These lesions can serve as an excellent model system for studying genetic changes associated with the inception of skin SCC. In the present study, five such lesions of the skin, three AKs and two AK+CIS, from three patients were short-term cultu

Thylakoids isolated from tobacco were fragmented by sonication and the vesicles so obtained were separated by partitioning in aqueous polymer two-phase systems. By this procedure, grana vesicles were separated from stroma exposed membrane vesicles. The latter vesicles could be further fractionated by countercurrent distribution, with dextran-polyethylene glycol phase systems, and divided into two

Popular Abstract in Swedish Denna islamologiska avhandling diskuterar och analyserar den islamtolkning som gjorts av den muslimske tänkaren Nurcholish Madjid i Indonesien. Nurcholish ¬ som nyligen dog vid sextisex års ålder - har bidragit till reformeringen av islamiskt tänkande i Indonesien i över trettio år. Hans idéer är starkt påverkade av den lokala indonesiska kontexten, men utgör också en dThis dissertation in the field of Islamic studies offers a critical analysis of Nurcholish Madjid's attempt to interpret Islam within the framework of modern Indonesia. Nurcholish, who recently passed away at the age of sixty-six, had been active in the reform of Islamic thought for over thirty years, and while remaining deeply coloured by the local Indonesian context, was also part of a global an

The main object of materials science and technology is relationships between structure and properties. The practical use of engineering materials also involves consideration of things other than current theories for such relationships. Uncertainties of various kinds prompt reflections on the validity and applications of common practice based on experience. Among other things, this is true for deci

Initial results from the XUV undulator beamline at the 4.5 GeV storage ring DORIS are reported. The beamline consists of three different undulators mounted on a revolver type device and a modified SX-700 plane grating monochromator with a spherical focusing mirror. It covers the spectral range from 50–2000 eV with excellent spectral resolution and high photon flux. In the energy range 400 eV to 1

The novel cytotoxic hexacyclic illudane-illudalane bis-sesquiterpene bovistol (la) was obtained from the basidiomycete Bovista sp. 96042, together with several new sesquiterpenes. la is formed in the fungus by a heteroatom Diels-Alder dimerisation of psathyrellon B (2). (C) 2002 Elsevier Science Ltd. All rights reserved.

Popular Abstract in Swedish Denna avhandling behandlar två ämnen inom trådlös kommunikation: interferens mellan frekvenshoppande (FH) nätverk och fleranvändardiversitet. I arbetet på FH nätverk undersöks ett system där frekvenshopp används för att möjliggöra samtidig tillgång till kanalen för multipla okoordinerade nätverk. Detta åstadkoms genom att frekvenshoppen sker varje gång ett ny paket skaThis thesis deals with two topics in wireless communications: interference between frequency-hopping (FH) networks, and multiuser diversity. The work on FH treats a system where FH is used to provide simultaneous access to the channel for multiple uncoordinated wireless networks. This is achieved by performing frequency hops on a packet-by-packet basis, and letting the sequence of hopping frequen

The mobile phone is one of the most widespread devices with rendering capabilities. Those capabilities have been very limited because the resources on such devices are extremely scarce; small amounts of memory, little bandwidth, little chip area dedicated for special purposes, and limited power consumption. The small display resolutions present a further challenge; the angle subtended by a pixel i