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Reproductive function in male childhood cancer survivors

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Målet med denna avhandling var att undersöka hur cancersjukdomar i barndomen och behandlingen av dessa påverkar olika aspekter av fortplantningsförmågan i vuxen ålder. Glädjande nog har andelen patienter som överlever cancer i barndomen de senaste decennierna ökat stadigt till nivåer som idag ligger på nästan 80%. Ökad överlevnad medfChildhood cancer (CC) survival rate has increased over the last couple of decades, today approaching 80%. Therefore more attention has been paid to late effects. One important issue for CC survivors (CCS) is impaired reproductive function. CC per se and/or its treatment can impair the reproductive ability by affecting sperm production, as well as by damaging sperm DNA. This is a matter of concern,

Carbon fluxes of xylose-consuming Saccharomyces cerevisiae strains are affected differently by NADH and NADPH usage in HMF reduction.

Industrial Saccharomyces cerevisiae strains able to utilize xylose have been constructed by overexpression of XYL1 and XYL2 genes encoding the NADPH-preferring xylose reductase (XR) and the NAD(+)-dependent xylitol dehydrogenase (XDH), respectively, from Pichia stipitis. However, the use of different co-factors by XR and XDH leads to NAD(+) deficiency followed by xylitol excretion and reduced prod

Orientational order in a glass of charged platelets with a concentration gradient

Colloidal dispersions of anisometric particles can display dynamical arrest and ordering involving both translational and rotational degrees of freedom. We show that orientational order can develop in glassy colloidal dispersions of charged platelets when a concentration gradient is imposed through solvent evaporation. Our model system of Laponite (LRD) platelets in deionized water has been extens

The corporatization process: An owner perspective

The purpose of the paper is to: i) explore how the ownership-relationship between the public authority and the provider of the service is organized and managed to secure accountability in those cases the ownership remains public ii) how the purchaser-provider relationship is organized and managed so that public value are protected and iii) to what extent NPM still influences the reforms conducted

Transport studies of electron-hole and spin-orbit interaction in GaSb/InAsSb core-shell nanowire quantum dots

We report low-temperature transport studies of parallel double quantum dots formed in GaSb/InAsSb core-shell nanowires. At negative gate voltages, regular patterns of Coulomb diamonds are observed in the charge stability diagrams, which we ascribe to single-hole tunneling through a quantum dot in the GaSb core. As the gate voltage increases, the measured charge stability diagram indicates the appe

Predicting future values of a random function

Prediction from time-series data is traditionally accomplished using parametric, or at least structural, methods. For example, after removing trends, arguing that the time-series is an autoregression, and estimating the autoregressive parameters, we may predict future expected values, conditional on the past. In this paper, motivated by long meteorological maximum-temperature time-series, we sugge

Exposure and toxic effects of elemental mercury in gold-mining activities in Ecuador

Traditional gold mining, using metallic mercury (Hg-0) to form gold amalgam, followed by burning to remove the Hg-0, is widely used in South America, Africa and Asia. The gold is sold to merchants who burn it again to eliminate remaining Hg-0. In Ecuador, 200 gold miners, 37 gold merchants and 72 referents were studied. The median Hg concentrations in urine (U-Hg) were 3.3 (range 0.23-170), 37 (3.

On the self-assembly of a tryptophan labeled deoxycholic acid

Self-assembly of peptides and bile acids has been widely investigated because of their biological role and their potential as a tool for the preparation of nanostructured biomaterials. We herein report both the synthesis and the self-association behavior of a compound that combines the aggregation properties of bile acid- and amino acid-based molecules. The derivative has been prepared by introduc

Work ability- Health professionals' perspectives and rehabilitation outcomes

Popular Abstract in Swedish Arbetsförmåga har kommit att bli ett viktigt begrepp i samhället, men också för individen. Det saknas i dag en tydlig definition av arbetsförmåga, trots att det har en stor inverkan på hur sjukförmåner distribueras och också för den enskilde individens möjlighet att försörja sig. I västvärlden är arbetsförmåga ofta diskuterat i relation till sjukskrivning och en åldrad The overall aim of this thesis was to deepen the understanding of work ability by analyzing how different health professionals experience and perceive work ability and assessments of work ability, and also by analyzing rehabilitation outcomes that are related to work ability. The focus has been on musculoskeletal disorders with associated psychosocial factors. Method. The general approach was indu

Getting it together-Interdisciplinary sound environment research.

The Sound Environment Center at Lund university is an interdisciplinary center created to coordinate research on sound and soundscape issues and is known to be the first of its kind worldwide. Ranging from acoustics to medicine, psychology, and cognitive sciences, as well as humanities like musicology and linguistics, soundscape research adresses many interdependent areas and touches upon health a

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Abstract in French Le monologue théâtral par l’auteur italien Alessandro Baricco, Novecento, publié en 1994 a fait l’objet de deux adaptations: en 1998 Giuseppe Tornatore a réalisé un film en langue originale anglaise, The Legend of the Pianist on the Ocean; en 2008, Baricco lui-même, en collaboration avec le dessinateur Giorgio Cavazzano et le scénariste Tito Faraci, signe l’adaptation en bandes

A combined experimental and computational study of supramolecular assemblies in ternary copper(II) complexes with a tetradentate N-4 donor Schiff base and halides

Three new copper(II) complexes, [Cu(L)(Cl)]ClO4 (1), [Cu(L)(Br)]ClO4 (2) and [Cu(L)(I)]ClO4 (3), have been prepared from a tetradentate symmetrical Schiff base, N,N'-bis-(1-pyridin-2-yl-ethylidene)-propane-1,3-diamine (L), and characterized by elemental analysis, IR and UV-Vis spectroscopy and single-crystal X-ray diffraction studies. Extended supra-molecular networks were generated through differ

Isolation of hemicelluloses by ultrafiltration of thermomechanical pulp mill process water-Influence of operating conditions

Hemicelluloses could be used to replace fossil-based materials in several high-value-added products. Today, vast amounts of hemicelluloses are discharged from pulp mills all over the world as waste, but these could be isolated by membrane filtration, and utilized in various applications. In this study, the hemicellulose galactoglucomannan was isolated from process water from a thermomechanical pul

Tunneling Anisotropic Magnetoresistance in Co/AlOx/Au Tunnel Junctions.

We observe spin-valve-like effects in nanoscaled thermally evaporated Co/AlO x /Au tunnel junctions. The tunneling magnetoresistance is anisotropic and depends on the relative orientation of the magnetization direction of the Co electrode with respect to the current direction. We attribute this effect to a two-step magnetization reversal and an anisotropic density of states resulting from spin-orb