Role of classical pro- and anti-inflammatory mediators in ischemic stroke. Beyond neuroimmunomodulation.
Stroke is a leading cause of death and long-term neurological deficits worldwide, and no effective treatment is available for the vast majority of the stroke patients. A rapid and persistent activation of multiple and dynamic inflammatory and immune cascades, in and outside the brain, occurs after stroke. These cascades are believed to affect the progression of the cerebral damage, as well as neur
