Popular Abstract in Swedish Den nyligen utvecklade microarray-tekniken gör det möjligt att mäta mängden av mRNA för tusentals gener samtidigt. För att tolka dessa data krävs statistiska metoder och denna avhandling behandlar tre sådana. Den första metoden är utvecklad för att skilja ut de gener vars mRNAmängd är olika stor i olika vävnadstyper. Den andra metoden är avsedd för att analysera och berIn this thesis, three aspects of gene expression data analysis are discussed: Differential gene expression is addressed by a probabilistic method. Gene annotation enrichment analysis is discussed in the context of multiple hypothesis testing and the choice of null hypothesis. The possibility of inferring the activity of cellular signaling pathways from microarray data is explored. The methods deve

Beginning in 2002, the Department of Health (DoH) n partnership with the National Institute of Clinical Excellence (NICE) began publishing guidelines for the evidenced-based care and treatment of individuals with specific psychiatric disorders. With few exceptions the first-line psychological treatment recommended in all of the guidelines was some form of CBT. The publications of these guidelines

In an exploratory investigation of personality patterns, Swedish air force pilots (n = 22) and ground officers (n = 14) were tested with the Creative Functioning Test, the Serial Color Word test, and the Spiral After-Effect Technique. The participants also answered open questions about their work and about creativity related items. Achievement ratings were made by their superior officers. An initi

The Homogeneous Charge Compression Ignition (HCCI) principle holds promise to increase efficiency and to reduce emissions from internal combustion engines. As HCCI combustion lacks direct ignition timing control and auto-ignition depends on the operating condition, control of auto-ignition is necessary. Since auto-ignition of a homogeneous mixture is very sensitive to operating conditions, a fast

We apply causal loop diagrams (CLD) to picture how complex societal scenarios can be understood in terms of interdependent drivers and mechanisms between actors from the public and private sectors respectively. And we show how un-sustainable scenarios can be understood in terms of insufficient balancing feed-back in the system. We apply the methodology to picture such imbalances as funda- mental d

Investigation of a novel condition monitoring approach, combining artificial neural network (ANN) with a sequential analysis technique, has been reported in this paper. For this purpose operational data from a Siemens SGT600 gas turbine has been employed for the training of an ANN model. This ANN model is subsequently used for the prediction of performance parameters of the gas turbine. Simulated

Sentiment analysis, or opinion mining, is the process of extracting sentiment from documents or sentences, where the expressed sentiment is typically categorized as positive, negative, or neutral. Many different techniques have been proposed. In this paper, we report the reimplementation of nine algorithms and their evaluation across four corpora to assess the sentiment at the sentence level. We e

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We focus on improving resilience of cloud services (e.g., e-commerce website), when correlated or cascading failures lead to computing capacity shortage. We study how to extend the classical cloud service architecture composed of a load-balancer and replicas with a recently proposed self-adaptive paradigm called brownout. Such services are able to reduce their capacity requirements by degrading us

Our presentation will try to clarify the differences between Postphenomenology and Postpositivism. Contemporary studies of technology and its relation to science are very much inspired by the works of Don Ihde and Bruno Latour.Updated February 2016.

Abstract is not available

By applying Doppler-free saturated absorption spectroscopy in the regime of high integrated sample absorption, high-contrast Doppler-free laser transmission signals can be obtained as demonstrated in experiments on the sodium D lines. Natural linewidth background-free signals are observed.