Popular Abstract in Swedish Trots ett sunt leverne med regelbunden motion och nyttig mat kan vi inte alltid förhindra risken att drabbas av vissa typer av cancer som till exempel hjärntumörer. Den vanligaste formen av elakartade hjärntumörer heter glioblastoma multiforme och är också den mest aggressiva. Symptomen varierar beroende på tumörens storlek och var i hjärnan den växer, och patienter kanGlioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor in adults. Despite standard treatment including surgery, radiotherapy and temozolomide (TMZ)-based chemotherapy, the prognosis for GBM patients is dismal, and there is a need for novel treatments. One possible therapeutic treatment modality presented here is immunotherapy, either alone or combined with in

Amorphous silica (ASi) carried in suspension by rivers is an important component in the global Si budget. Water erosion processes in cultivated catchments are likely to drive ASi delivery to the river system. However, no studies have investigated the controls on ASi mobilization by erosional processes in croplands. Rainfall experiments were performed on split fields (i.e. a part conventionally plo

Single-shot time-of-flight spectra for Coulomb explosion of N-2 and I-2 molecules have been recorded at the Free Electron LASer in Hamburg (FLASH) and have been analysed using a partial covariance mapping technique. The partial covariance analysis unravels a detailed picture of all significant Coulomb explosion pathways, extending up to the N4+-N5+ channel for nitrogen and up to the I8+-I9+ channe

An experimental investigation was performed for convective condensation of R410A inside one smooth tube (3.78 mm, inner diameter) and six microfin tubes (4.54, 4.6 and 8.98 mm, fin root diameter) of different geometries for mass fluxes ranging from 99 to 603 kg m-2s-1. The experimental data were analyzed with updated flow pattern maps and evaluated with existing correlations. The heat transfer coe

Wireless sensor networks are emerging as an important area for communications. They enable a wealth of new applications including surveillance, building control, factory automation, and in-vehicle sensing. The sensor nodes have to operate under severe constraints on energy consumption and form factor, and provide the ability for precise self-location of the nodes. These requirements can be fulfill

Background: Microarray gene-profiling of invasive breast cancer has identified different subtypes including luminal A, luminal B, HER2-overexpressing and basal-like groups. Basal-like invasive breast cancer is associated with a worse prognosis. However, the prognosis of basal-like ductal carcinoma in situ (DCIS) is still unknown. Our aim was to study the prognosis of basal-like DCIS in a large pop

When a child is diagnosed with diabetes, the symptoms may be in its most severe form with ketoacidosis, to mild symptoms of diabetes, detected incidentally. Moderate and severe symptoms of diabetes presentation require infusion therapy and thereby necessitate hospitalisation for the first few days. The initial management is largely a preparation for family members to help them gain the practical u

The Greenland ice core from NorthGRIP (NGRIP) contains a proxy climate record across the Pleistocene-Holocene boundary of unprecedented clarity and resolution. Analysis of an array of physical and chemical parameters within the ice enables the base of the Holocene, as reflected in the first signs of climatic warming at the end of the Younger Dryas/Greenland Stadial 1 cold phase, to be located with

Current theory suggests that mass change in adult birds while breeding may be adaptive (to reduce wing-loading during nestling feeding) or result from physiological stress. To test which might be more important in determining mass loss in breeding Savi's Warblers (Locustella luscinioides), we used a new approach in which the variation in four indices of body condition was described: weight, fat sc

Ten rhenium carbonyl complexes-[Re(H)(CO)(3)(1a)], [Re-3(mu-H)(3)(CO)(10) (1a)], [Re-2(CO)(9)(2a)], [Re-2(CO)(8)(2a)], [Re-2(CO)(9)(2b)], [{Re-2(CO)(9)}(2)(2b)], [Re-2 (CO)(8)(2b)], [Re-2(CO)(8)(1b)], [Re-2(mu-H)(2)(CO)(6)(2b)] and [Re-3(mu-H)(3)(CO)(11)(2b)]-containing different bidentate chiral phosphine ligands of the Josiphos (1a, 1b) and Walphos (2a, 2b) families have been synthesized and ful

Background: Overweight and obesity in younger children could better be brought in focus through a deeper understanding of how Child Health Care nurses (CHC-nurses) perceive their work with the problems of overweight at the CHC Centers. The aim of this study was to elucidate the CHC-nurses conceptions of their preventive work with childhood overweight and obesity in Child Health Care. Method: A qua

Ljusforskning är om något diversifierad och omfattar teorier och metoder från skilda discipliner som teknik, medicin och samhällsvetenskap. Det finns också en förväntan att erhållna forskningsresultat skall kunna appliceras direkt i verkliga miljöer. I och med introduktionen av LED har många tidigare studier som behandlat glödlampor, lysrör och andra ljuskällor inaktualiserats. Ny kunskap - och nyLighting research is diversified and includes theory and methodology from disciplines as different as technology, medicine and social sciences. There is also an expectation on research results to be directly applicable in real environments. The introduction of LED has furthermore made previous research on incandescent lamps, fluorescent lamps and other light sources, outdated. New knowledge – and

The term molecular object (MO) is introduced to describe single, shape persistent macromolecules that retain their form and mesoscopic dimensions irrespective of solvent quality and adsorption onto a surface. The concept is illustrated with results concerning homologous series of dendronized polymers (DP). In particular, we discuss imaging experiments quantifying deformation upon adsorption, defec