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Time transformation and reversibility of Nambu–Poisson systems

A time transformation technique for Nambu–Poisson systems is developed, and its structural properties are examined. The approach is based on extension of the phase space P into P¯ = P×R, where the additional variable controls the time-stretching rate. It is shown that time transformation of a system on P can be realised as an extended system on P¯, with an extended Nambu–Poisson structure. In addi

Elevated glucose levels promote contractile and cytoskeletal gene expression in vascular smooth muscle via Rho/protein kinase C and actin polymerization.

Both type 1 and type 2 diabetes are associated with increased risk of cardiovascular disease. This is in part attributed to the effects of hyperglycemia on vascular endothelial and smooth muscle cells but the underlying mechanisms are not fully understood. In diabetic animal models, hyperglycemia results in hyper-contractility of vascular smooth muscle possibly due to increased activation of Rho-k

Pancreatic cancer: Translational research aspects and clinical implications.

Despite improvements in surgical techniques and adjuvant chemotherapy, the overall mortality rates in pancreatic cancer have generally remained relatively unchanged and the 5-year survival rate is actually below 2%. This paper will address the importance of achieving an early diagnosis and identifying markers for prognosis and response to therapy such as genes, proteins, microRNAs or epigenetic mo

Using business intelligence to prevent and solve crime in Wallander land

Actor network theory (ANT) and sociomateriality are two influential information systems(IS) entanglement perspectives. El Sawy identified three faces of IS views: connection,immersion, and fusion. To elaborate the three views, we adopt relational emergence theory, based on the philosophy of critical realism, to better describe and explain the shifts in IS from connection to immersion and finally t

Putting co-workers in the limelight: New challenges for communication professionals

The status of co-workers has increased due to the expansion of post-bureaucratic and knowledge-intensive organizations. In organization studies the importance of co-workers has for a rather long time been acknowledged. Remarkably has co-workers more or less been neglected in research as well as in practice within the field of strategic communication. In research the overall focus is mainly on the

Cerebellar Synaptic Plasticity and the Credit Assignment Problem.

The mechanism by which a learnt synaptic weight change can contribute to learning or adaptation of brain function is a type of credit assignment problem, which is a key issue for many parts of the brain. In the cerebellum, detailed knowledge not only of the local circuitry connectivity but also of the topography of different sources of afferent/external information makes this problem particularly

Adaptation and vision change the relationship between muscle activity of the lower limbs and body movement during human balance perturbations.

OBJECTIVE: Investigate the relationship between changes in lower limb EMG root mean square (RMS) activity and changes in body movement during perturbed standing. Specifically, linear movement variance, torque variance and body posture were correlated against tibialis anterior and gastrocnemius RMS EMG activity during perturbed standing by vibration of the calf muscles. METHODS: Eighteen healthy pa

Consanguinity and genetic diseases in North Africa and immigrants to Europe.

Endemic diseases are caused by environmental and genetic factors. While in this special issue several chapters deal with environmental factors, including infections, the present focus is on genetic causes of disease clustering due to inbreeding and recessive disease mechanisms. Consanguinity is implying sharing of genetic heritage because of marriage between close relatives originating from a comm

OH regeneration from methacrolein oxidation investigated in the atmosphere simulation chamber SAPHIR

Hydroxyl radicals (OH) are the most important reagent for the oxidation of trace gases in the atmosphere. OH concentrations measured during recent field campaigns in isoprene-rich environments were unexpectedly large. A number of studies showed that unimolecular reactions of organic peroxy radicals (RO2) formed in the initial reaction step of isoprene with OH play an important role for the OH budg

The Women's Health in the Lund Area (WHILA) study-An overview.

The Women's Health in the Lund Area (WHILA) study invited all women (n=10,766) living in the Lund area of Southern Sweden by 1995, who were born between 1935 and 1945. The health screening program included a postal validated questionnaire concerning medical history, drug treatment, family history of diabetes and hypertension, menopausal status, smoking and alcohol habits, education, household, and

Gene therapy for Parkinson's disease.

The once fantastic theoretical concept that patients with Parkinson's disease (PD) would receive gene therapy in an attempt to alleviate their symptoms and potentially modify the course of their disease has become a reality. On the basis of positive preclinical data, four different gene therapy approaches are currently in Phase I or Phase II clinical trials. Some approaches are intended to increas

A Method for Arterial Diameter Change Measurements Using Ultrasonic B-Mode Data.

Arterial diameter change is related to distending blood pressure and is used in estimation of arterial stiffness parameters. A common technique to track the arterial walls is by integration of wall velocities estimated by different methods using cross correlation or tissue Doppler. However, because of the high pulse repetition frequency and the need for separate pulsing sequences, the B-mode image

Seven Categories of Constitutional Critical Judging: An Interpretation of Nordic Case-Law

In Danish literature from the early 1970s, it was suggested that the freedom of speech should have a preferred position in relation to other constitutional rights. In a case from the Norwe-gian Supreme Court in 1976, judicial review of the constitutionality of legislation was divided in three categories. Constitutional rules about the freedom and security of the individual should be supervised mos

Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics.

Specification and differentiation of neural precursors into dopaminergic neurons within the ventral mesencephalon has been subject to much attention due to the implication of dopaminergic neurons in Parkinson's disease and the perspective of generating sources of therapeutically active cells to be used for cell replacement therapy for the disease. However, despite intensive research efforts, littl

Is cartilage sGAG content related to early changes in cartilage disease? Implications for interpretation of dGEMRIC.

OBJECTIVE: This study investigates sulphated glycosaminoglycans (sGAG) content changes in early osteoarthritis (OA), and whether contrast-enhanced magnetic resonance imaging (MRI) of cartilage in vitro may identify early event of OA pathology. METHOD: Osteochondral plugs from patients with hip OA or femoral neck fracture (reference group) were collected and analysed by 1.5 T MRI with ΔR1 as a me

The Experience of Care at Nurse-Led Rheumatology Clinics.

OBJECTIVE: To describe how people with rheumatoid arthritis (RA) experience the care provided by Swedish nurse-led rheumatology outpatient clinics. METHODS: Eighteen adult people with a diagnosis of RA who had had at least three documented contact sessions with a nurse-led clinic were interviewed. The interviews were analysed with qualitative content analysis. RESULTS: Care was expressed in