En majoritet av de nordliga torvmarkerna utvecklades under holocen som ett resultat av en positiv massbalans mellan nettoprimärproduktion och heterotrofa nedbrytningshastigheter. Sedan dess har de lagrat stora mängder kol i terrestra ekosystem. En betydande del av dessa områden sammanfaller också med regioner med underliggande permafrost och uppvisar olika ackumulationsmönster av torv. Således, föThe majority of the northern peatlands developed during the Holocene as a result of a positive mass balance between net primary productivity (NPP) and heterotrophic decomposition rates. Over that time they have sequestered a huge amount of carbon in terrestrial ecosystems. A significant proportion of these areas also coincides with areas underlain with permafrost and shows a diverse range of peat

Impaired cholesterol/lipoprotein metabolism is linked to neurodegenerative diseases such as Alzheimer's disease (AD). Cerebral cholesterol homeostasis is maintained by the highly efficient blood-brain barrier (BBB) and flux of the oxysterols 24(S)-hydroxycholesterol and 27-hydroxycholesterol, potent liver-X-receptor (LXR) activators. HDL and their apolipoproteins are crucial for cerebral lipid tra

Binary rare gas clusters; xenon and neon which have a significant contrariety between sizes, produced by a co-expansion set up and have been studied using synchrotron radiation based x-ray photoelectron spectroscopy. Concentration ratios of the heterogeneous clusters; 1%, 3%, 5% and 10% were controlled. The core level spectra were used to determine structure of the mixed cluster and analyzed by co

The Djamgyr gold deposit is located within the Neoproterozoic basement of the Middle Tien Shan terrane immediately west of the Talas-Fergana fault. The deposit comprises a system of auriferous quartz veins cross-cutting the Beshtor plagiogranite. The veins are surrounded by hydrothermal alteration aureoles and are oriented parallel to the Talas-Fergana fault. The Beshtor granite sampled in the vic

The ductility of Al alloys is dictated by the nucleation, growth and coalescence of small internal voids originating from intermetallic particle fracture and from the presence of pre-existing porosity. The ductility is degraded when intermetallic particles are large and clustered. A low ductility adversely impacts both forming operations and the integrity of structural components. Local stirring u

Aims: Patterns of species richness, such as the remarkable biodiversity of tropical regions, have been documented and studied for centuries. However, their underlying evolutionary and ecological causes are still incompletely understood. A commonly stated paradigm in the literature is that high richness in some habitats is directly caused by one of three competing explanations: (1) greater time-for

Ozone and nitrogen oxides (NOx) are air pollutants with known associations to adverse health effects on humans. Few studies have simultaneously measured ozone and nitrogen oxides with high spatial resolution. The main aim of this paper was to assess the levels and variation of ground-level ozone, NO2 and NOx in two Swedish cities. An additional aim was to describe the levels of these pollutants wi

Synthetic glucocorticoids (GCs) are widely used in the variety of dosages for treatment of premature infants with chronic lung disease, respiratory distress syndrome, allergies, asthma, and other inflammatory and autoimmune conditions. Yet, adverse effects such as glucocorticoid-induced osteoporosis and growth retardation are recognized. Conversely, 2-oxoglutarate (2-Ox), a precursor of glutamine,

Several studies on pregnancy-Associated cancers have suggested an association with congenital anomalies in offspring. Previous studies have included maternal cancers diagnosed up to 2 years after pregnancy; however, long latency periods of some cancers mean that cancers diagnosed many years postpartum might have been present during pregnancy in a preclinical state. This paper considers the associa

Detta PM föreslår ett första ramverk för begreppet tillitsbaserad styrning. En teoretisk och en praktisk definition av tillitsbaserad styrning föreslås. Baserat på en klassisk modell från den internationella tillitsforskningen antas tilliten utgå från en bedömning av tillitsvärdigheten hos motparten, givet dennes förmåga (kunskap, m.m.), dennes integritet och dennes hjälpvillighet. Det slås vidare

Adhesion is a key component of hematopoietic stem cell regulation mediating homing and retention to the niche in the bone marrow. Here, using an RNA interference screen, we identify cytohesin 1 (CYTH1) as a critical mediator of adhesive properties in primary human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Knockdown of CYTH1 disrupted adhesion of HSPCs to primary human mes

MicroRNAs (miRNAs) are cellular, short, non-coding ribonucleotides acting as endogenous posttranscriptional repressors following incorporation in the RNA-induced silencing complex. Despite being chemically and mechanistically very similar, miRNAs exert a multitude of different cellular effects by acting on mRNA species, whose gene-products partake in a wide array of processes.Here, the aim was to