The astrological doctrines of aspects and planetary dignities found in the authoritative texts of the Tājika (Sanskritized Perso-Arabic) school are examined with respect to their origins and historical development, with particular emphasis on Balabhadra’s encyclopaedic Hāyanaratna (1649) and its quotations from the perhaps earliest work of the school, Samarasiṃha’s Tājikaśāstra (thirteenth century

This paper supplements and corrects the information given in the works of David Pingree regarding four major authors on Tājika or Sanskritized Perso-Arabic astrology from the fourteenth to the seventeenth century: Tejaḥsiṃha, Yādavasūri, Bālakṛṣṇa and Balabhadra. It further contributes information on a fifth such author, Tuka, not discussed by Pingree.

The highly popular Praśnatantra attributed to Nīlakaṇṭha of Kāśī (fl. late 16th century) and sometimes regarded as the third volume of his Tājikanīlakaṇṭhī is shown to depend for its basic structure on an abridged Sanskrit version of the Kitāb fi l-masāʾil wa-l-aḥkām by Sahl ibn Bishr (early 9th century), apparently authored by Samarasiṃha in the 13th century, to which quotations primarily from Sa

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Serine hydroxymethyltransferase (SHMT) is the major source of 1-carbon units required for nucleotide synthesis. Humans have cytosolic (SHMT1) and mitochondrial (SHMT2) isoforms, which are upregulated in numerous cancers, making the enzyme an attractive drug target. Here, we show that the antifolates lometrexol and pemetrexed are inhibitors of SHMT2 and solve the first SHMT2-antifolate structures.

Beslutsfattare bör inse betydelsen av butikers vara eller inte vara för samhällets utveckling innan det är för sent, skriver Karin M Ekström, professor i företagsekonomi, och Håkan Jönsson, docent i etnologi.

Occupational well-being is a central issue underpinning factors that constitute a good life. This study aimed to explore occupational well-being among Middle Eastern immigrants to Sweden, as reflected in the occupations performed in the context of psychosocial health care. Ten participants experiencing mental health issues, who received occupation-based rehabilitation, were interviewed. Grounded t

There is a scarcity of rehabilitation methods for people with stress-related disorders that are effective in terms of return to work and reducing sick leave. This chapter describes the Redesigning Daily Occupations (ReDOTM) program for women with stress-related disorders, the development, its main principles, and primary and secondary outcomes. The ReDOTM program, which addresses people’s whole re

Due to the great variation in approaches to psychiatric rehabilitation, the literature does not provide a uniform description of these methods. In this review, outcomes in terms of subjective quality of life are discussed in relation to vocational training, activity-based rehabilitation, case management, and social skills training. Relationships between aspects of daily life and subjective quality

Twenty patients, receiving group based psychiatric outpatient occupational therapy, were assessed at admission and discharge regarding psychiatric symptoms (SCL-90-R), global mental health (HSRS), quality of life (SQoL), and occupational performance (AOF). The patients were in treatment from 4 to 30 months. There were statistically significant improvements from admission to discharge on all variab

"Homo deus: a short history of the future", Yuval Noah Harari's book discusses the sources of power of modern man, beginning especially after the Second World War. The starting approach is the Enlightenment-specific, glorifying progress and then follow optimistic conclusions for the future. The impression is of progressive euphoria, but it is true that sometimes the jubilation is suspended and the

Background: People with psychiatric disabilities often struggle with maintaining a satisfying occupational balance. Knowledge about factors of relevance for occupational balance in this group is therefore vital for improving their support.Aim: The aim was to describe perceptions of occupational balance among people with psychiatric disabilities living in supported housing (SH) or in own flat/house

Research indicates that occupation is important for well-being in people with mental illness, but this has not been extensively studied among those with severe psychiatric disabilities. Social contacts may possibly play a more vital role for them. This study aimed to explore how aspects of occupation and social interaction were related with well-being factors in that group, while controlling for t

Objective: People who suffer from psychiatric illness have a more than doubled lifetime risk of acquiring an alcohol or drug use disorder. Furthermore, hazardous substance use impairs treatment outcomes and protracts the duration of illness among people with mental disorders. The aim of this study was to investigate substance use among people with psychiatric disabilities receiving municipality-ba

Satisfaction with everyday occupations has been shown to be important for health and well-being in various populations. Research into satisfaction with everyday occupations among elderly persons is, however, lacking. The aim was to investigate the psychometric properties of an adapted test version of the Satisfaction with Daily Occupations instrument (SDO) for elderly people, called SDO-E. Five ho

This case study investigates the implementation of a free-choice market system in community mental health services using the example of day centres for people with psychiatric disabilities. It was conducted in a major city that was about to implement a free-choice market system due to a new legislation that made it feasible. Eighteen semi-structured interviews were conducted. Agents situated in di