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The HIV-1 capsid protein, p24 antigen, is of considerable diagnostic interest because following HIV exposure it is detectable several days earlier than host-generated HIV antibodies (which are the target of almost all current tests used in the field) and can be used to design very sensitive assays without the need for PCR. Here, we present an ultrasensitive capacitive immunosensor that is capable
This study investigates the retention of different sized ultra-small superparamagnetic iron oxide nanoparticles (USPIOs) in lymph nodes of healthy rats, after subcutaneous injection. Three distinct sizes (15, 27 and 58 nm) of USPIOs were synthesized by only varying the thickness of the polymer coating surrounding the 10 nm cores. Particles were injected on the dorsal side of the hind paw of rats a
The use of light emitting diodes (LEDs) in outdoor lighting has energy-saving potential, but users' responses to this light source are largely unknown. An intervention study in two residential areas compared conventional lighting installations (high pressure sodium in Area 1 and high pressure mercury in Area 2) to a retrofitted LED-alternative regarding residents' perceptions of quality of light,
Abstract is missing (Short Communication).
Some observational evidence-such as bimodal drop size distributions, comparatively high concentrations of supercooled drops at upper levels, high concentrations of small ice crystals in cloud anvils leading to high optical depth, and lightning in the eyewalls of hurricanes-indicates that the traditional view of the microphysics of deep tropical maritime clouds requires, possibly, some revisions. I
The purpose was to estimate the proportion of current open aortic arch reconstructions that might be feasible for endovascular repair. From all elective repair made in Southern Sweden in one center between 2005 and 2012, 129 open and eight endovascular aortic arch repairs were identified. The anatomy of the ascending arch and descending aorta as well as the arch vessels was categorized from multip
A crucial requirement in the development of liquid-metal spallation neutron target is knowledge of the composition and amount of volatile radionuclides that are released from the target during operation. It is also important to know the total amount produced, which could be released if there was an accident. One type is the lead-bismuth eutectic (LBE) target where different radionuclides can be pr
Synthetic molecular motors typically take nanometer-scale steps through rectification of thermal motion. Here we propose Inchworm, a DNA-based motor that employs a pronounced power stroke to take micrometer-scale steps on a time scale of seconds, and we design, fabricate, and analyze the nanofluidic device needed to operate the motor. Inchworm is a kbp-long, double-stranded DNA confined inside a n
An acute meal study was performed to determine postprandial glucose and insulin responses after consumption of two fermented oat bran-based beverages (with and without exopolysaccharides) and yoghurt. This randomized, single-blind, within-subject study included 18 healthy, overweight participants. Four breakfast meals, including a reference meal, were tested; all meals contained 50 g of available
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated ∼2,000, ∼3,700 and ∼9,500 SNPs explained ∼21%, ∼24% and ∼29% of phenotypic variance. Furthermore, all common variants
This paper presents a Sorted QR-Decomposition (SQRD) processor for 3GPP LTE-A system. It achieves energy efficiency by co-optimizing techniques, such as heterogeneous processing, reconfigurable architecture, and dual-supply voltage operation. At algorithm level, a low-complexity hybrid decomposition scheme is adopted, which switches, depending on the energy distribution of spatial channels, betwee
Isolated tumour cells and micrometastases represent two different staging categories and are often dealt with differently when identified in sentinel lymph nodes of breast cancer patients. The reproducibility of these categories was found to be suboptimal in several studies. The new edition of the TNM (Tumour Node Metastasis) is expected to improve the reproducibility of these categories. Fifty ca
Synaptic pathology occurs early in Alzheimer's disease (AD) development, and cerebrospinal fluid biomarkers for synaptic damage may be altered early in the disease process. In the present study we examined cerebrospinal fluid levels of the postsynaptic protein neurogranin in patients with mild cognitive impairment (MCI) or AD and controls. The low neurogranin level in cerebrospinal fluid required
With global warming, snowmelt is occurring earlier and growing seasons are becoming longer around the Arctic. It has been suggested that this would lead to more uptake of carbon due to a lengthening of the period in which plants photosynthesize. To investigate this suggestion, 8 consecutive years of eddy covariance measurements at a northeastern Siberian graminoid tundra site were investigated for
Asperger syndrome (AS) and non-verbal learning disability (NLD) are both characterized by impairments in motor coordination, visuo-perceptual abilities, pragmatics and comprehension of language and social understanding. NLD is also defined as a learning disorder affecting functions in the right cerebral hemisphere. The present study investigates if individuals with AS and a cognitive profile consi
In the Next-to-Minimal SuperSymmetric Model (NMSSM) the lightest CP-odd Higgs bosons (a(1)) can be very light. As a consequence, in addition to the standard charged Higgs boson (h(+/-)) decays considered in the MSSM for a light charged Higgs (m(h +/-) < m(t)), the branching fraction for h(+/-) -> a(1)W can be dominant. We investigate how this signal can be searched for in t<(t)over bar> production
Satellite remote sensing has the potential to contribute to plant phenology monitoring at spatial and temporal scales relevant for regional and global scale studies. Historically, temporal composites of satellite data, ranging from 8 days to 16 days, have been used as a starting point for satellite-derived phenology data sets. In this study we assess how the temporal resolution of such composites
With its unprecedented light-collecting area for night-sky observations, the Cherenkov Telescope Array (CTA) holds great potential for also optical stellar astronomy, in particular as a multi-element intensity interferometer for realizing imaging with sub-milliarcsecond angular resolution. Such an order-of-magnitude increase of the spatial resolution achieved in optical astronomy will reveal the s
Galactic bulges are central to understanding galaxy formation and evolution. Here we report on recent studies using micro-lensing events to obtain spectra of high resolution and moderately high signal-to-noise ratios of dwarf stars in the Galactic bulge. Normally this is not feasible for the faint turn-off stars in the Galactic bulge, but micro-lensing offers this possibility. Elemental abundance
