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Adenocarcinoma of the small intestine (ASI) is a rare disease of unknown aetiology. The glutathione S-transferase M1 (GSTM1) enzyme catalyses the detoxification of compounds involved in carcinogenesis of adenocarcinoma of the stomach, colon and lung, including constituents of tobacco smoke. We investigated a possible interaction between the lack of GSTM1 enzyme activity and the carcinogenic compou
Diabetes is caused by an absolute (type 1) or relative (type 2) deficiency of insulin-producing beta cells. We have disrupted expression of the mitochondrial protein frataxin selectively in pancreatic beta cells. Mice were born healthy but subsequently developed impaired glucose tolerance progressing to overt diabetes mellitus. These observations were explained by impairment of insulin secretion d
Background: The association between nasal and bronchial symptoms, and the course of bronchial responsiveness and airway inflammation in house dust mite sensitive persistent rhinitis over a prolonged time period has not been thoroughly explored. Objective: To determine if nasal symptoms were associated with bronchial symptoms in persistent rhinitic subjects, and to assess their bronchial responsive
This study outlined the influence of a number of parameters affecting the emission rate from one of the largest sources of VOC in the building stock in the Nordic countries. This source is flooring systems of polyvinyl chloride or linoleum attached to a substrate of moisture damaged or insufficiently dried concrete. The secondary emission rate of degradation products was measured, with the Field a
We present statistical evaluations of wideband spatial dual-polarized radio channel measurements. Some 80 different street-level transmitter positions in downtown Helsinki, Finland, were measured. We chose three different receiver array sites below, at, and above the roofop level of the surrounding urban environment. A super-resolution algorithm allows the determination of the directions of arriva
The aim Of this Study was to determine the effects of dexamethasone (Dex) and alpha-ketoglutarate (AKG) oil the total cholesterol, glucose, Na+, Cl-, total Ca and K+ levels, in serum for newborn and neonate piglets. The blood samples were collected from newborn non-suckling piglets born by sows administered front the 91(st) d of pregnancy to the parturition With AKG and/or Dex (AKG-0.4 g/kg b.w./e
Fire fighting work comprises work tasks requiring an energy yield at maximal or close to maximal levels of the individual. Due to the very nature of fire fighting more complex physiological variables are difficult to measure. We measured metabolic and respiratory responses in 15 male.. professional fire fighters during simulated work tasks on a test ground. Work time was on the average 22 min with
The effects of nicotine administration (2 mg eight-times daily as nicotine chewing gum for two weeks) on plasma lipid and lipoprotein concentrations were studied in young healthy volunteers. Plasma levels of the nicotine metabolite, cotinine, reached levels comparable to those seen in smokers. Plasma concentrations of triglyceride, cholesterol, HDL cholesterol, LDL cholesterol, and apolipoproteins
This article discusses why films have not been used more than they have as historical sources and argues that films ought to be used more by historians. Principally, historians can use film in three basic ways, all of which give access to information about the period when it was produced. First, films can with caution be used for information about the persons, objects and events depicted in docu
beta-Carbolines show structural resemblance to the neurotoxic N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and are metabolized to mitochondrial toxicants. Humans are continuously exposed to low levels of beta-carbolines through cooked food, coffee, alcoholic beverages and tobacco smoke. beta-Carbolines have previously been detected in higher levels in the pigmented substantia nigra than in the cor
A fairly large study of attitudes towards mathematics among Swedish students at secondary level was conducted during 2001–2004. A newly developed instrument was used that was designed to capture gender stereotyped attitudes among students related to various aspects of mathematics in education and future life. The new scale and its development are described with reference to the original Australian
Three microperoxidases-hemin-6(7)-gly-gly-his methyl ester (HGGH), mesohemin-6(7)-gly-gly-his methyl ester (MGGH) and deuterohemin-6(7)-gly-gly-his methyl ester (DGGH)-have been prepared as models for heme-containing peroxidases by condensation Of glycyl-glycyl-L-histidine methyl ester with the propionic side chains of hemin, mesohemin and deuterohemin, respectively. The three microperoxidases dif
The aggravating effect of hyperglycemia on ischemic brain injury can be mimicked in a model of in vitro ischemia (IVI) using murine hippocampal slice cultures. Using this model, we found that the damage in the CA1 region following IVI in the absence or presence of 40 mM glucose (hyperglycemia) is highly temperature dependent. Decreasing the temperature from 35 to 31 degrees C during IVI prevented
Popular Abstract in Swedish Med ett historiskt perspektiv analyserar denna avhandling erfarenheter och identitetsskapande processer hos en grupp kvinnliga arbetare, cashewarbeterskor, i den sydindiska delstaten Kerala-välkänd för dess radikala befolkning och höga sociala indikatorer för invånarna. Cashewarbeterskorna utmanar den stereotypa bilden av kvinnor i ?Tredje Världen?, genom att de sedan 1Since the 1930s female cashew workers have constituted a majority of the registered workers in the South Indian State of Kerala and today number some 200,000. This group challenged the stereotypical view of Third World women because they were organized into unions, worked in the formal sector, and were literate. The background for this thesis has been the ?Kerala Model?, i.e., the political contex
