Accelerated cellular aging and reduced lifespan have recently been shown in birds chronically infected with malaria parasites. Whether malaria infection also affects cellular aging in humans has not been reported. Here, we assessed the effect of a single acute Plasmodium falciparum malaria infection on cellular aging dynamics in travelers prospectively followed over one year in Sweden. DNA and RNA

Liposomes are considered a major route for encapsulation of hydrophilic and hydrophobic molecules. Chitosan coated liposomes could represent an alternative way as a carrier for delivery of drugs in human body. In this study the preparation and applicability of chitosan-coated liposomes containing curcumin as well as curcumin loaded anionic liposomes were evaluated. The applicability of the carrier

The study assesses the performance of experimental wetland pond systems vegetated by Lemna minor L. (common duckweed or lesser duckweed) for textile azo dye removal. The objectives are to assess the influence of L. minor on water quality parameters, compare the dye and chemical oxygen demand (COD) removal of four dyes (Acid Blue 113, Reactive Blue 198, Direct Orange 46 and Basic Red 46) with each

We argue that the meanings of demonstratives and articles can be analysed in terms of a combination of the spatial domain and a small set of semantic domains. We propose that deictic terms have a 'fast semantics' in the sense that they get their meaning in the course of the communicative act, as a result of an interaction between the interlocutors, which ultimately leads to referential anchoring.

The neural cells and factors determining normal vascular growth are not well defined even though vision-threatening neovessel growth, a major cause of blindness in retinopathy of prematurity (ROP) (and diabetic retinopathy), is driven by delayed normal vascular growth. We here examined whether hyperglycemia and low adiponectin (APN) levels delayed normal retinal vascularization, driven primarily b

Reprogramming of cellular identity using exogenous expression of transcription factors (TFs) is a powerful and exciting tool for tissue engineering, disease modeling, and regenerative medicine. However, generation of desired cell types using this approach is often plagued by inefficiency, slow conversion, and an inability to produce mature functional cells. Here, we show that expression of constit

Meteorites have captured our fascination since our early history-they have evoked awe, fear, an irresistible curiosity, and numerous lively debates. Former historians have indicated that many of the ancient cultures and civilizations in Europe, Africa, Asia, the Inuit, and the native Indians in America regarded both the meteorite and the location of their fall as sacred. Thus, they used the meteor

The Kago deposit is a small deposit located at the southern tip of the Satsuma Peninsula of Southern Kyushu, Japan. It lies proximal to the well-known Nansatsu-type mineralisation province dominated by high-sulfidation type epithermal deposits. The deposit was heavily mined in the 18 th Century, largely for its relatively higher gold compared to that of surrounding and regional deposits. The Kago

Escalation (macroevolutionary increase) or divergence (disparity between relatives) in trait values are two frequent outcomes of the plant-herbivore arms race. We studied the defences and caterpillars associated with 21 sympatric New Guinean figs. Herbivore generalists were concentrated on hosts with low protease and oxidative activity. The distribution of specialists correlated with phylogeny, pr

This book, the concluding book in a series of three, analyses the Hebrew word chesed. This word is often translated into English as “grace” or “mercy”, but it can also be understood as, e.g., “solidarity”, “covenantal loyalty” and “generosity”. The book also addresses the dichotomy “law and grace”, and especially how some understandings of these theological concepts may need to be redefined, refin

A comparison was made between two plant peroxidases, cationic horseradish peroxidase (HRP) and anionic tobacco peroxidase (TOP), combined with a highly cationic osmium polymer [Os(4,4'-dimethyl-2,2'-bipyridine)2poly(N-vinylimidazole)10Cl]+2/+ ([Os(dmp)PVI]+/2+) to develop highly sensitive, stable and selective hydrogen peroxide biosensors. The two different plant peroxidases were individually immo

BACKGROUND: Lymphedema leads to adipose tissue deposition. Water-fat magnetic resonance imaging (MRI) can quantify and localize fat and water. The presence of excess fat and excess water/muscle in the subfascial compartment of the lymphedematous limb has not been investigated before. The aim of this study was to investigate epifascial and subfascial fat and water contents in patients with chronic

Most spatiotemporal studies treat spatial and temporal analysis separately. However, spatial and temporal changes occur simultaneously and are correlated. In this study, we propose a generic framework to simultaneously analyse the spatial and temporal variations of water quality on a catchment scale. Specifically, we analyse the heterogeneity of temporal evolution of water quality data among diffe

In this study, an innovative idea of using a plane circular raft surrounded by a water tank is tested numerically using finite element simulations and compared with a conventional piled foundation concerning the geotechnical behavior. Cost comparisons are done for two foundation solutions. An observed soil profile found in Port-Said region in Egypt is used. The soil profile is implemented in the F