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The analytical distinction between critical and problem-solving research is useful. At the onset of research, the latter takes the world as it is while the former questions it. Yet, in striving to integrate social and natural dimensions of sustainability such a distinction may surface as a methodological obstacle. We illustrate how combining critical with problem-solving approaches can help us ima
Adult humans spontaneously associate visual features, such as size and direction of movement, with phonetic properties like vowel quality and auditory pitch. A number of recent studies have claimed that looking time in preverbal infants reveals the same associations, which would indicate that some cross-modal correspondences are the result of perceptual biases. Here we tested 30 infants of age 7-1
Design for fire safety may be carried out by two generic approaches - a set of prescriptive rules or by a performance-based approach where analytical tools are used to verify fire safety towards a set of functional requirements and performance criteria given by the building code. Normally, these two methods are mixed when design fire safety within a building. The option to apply fire safety engine
The assumption of linear confinement leads to a proportionality of the energy–momentum and space–time pictures of fragmentation for a simple q q ¯ system in the Lund string model. The hadronization of more complicated systems is more difficult to describe, and in the past only the energy–momentum picture has been implemented. In this article also the space–time picture is worked out, for open and
BACKGROUND: Long-term cognitive problems are common among elderly patients after surgery, and it has been suggested that inhalation anaesthetics play a role in the development of dementia. This study aims to investigate the hypothesis that patients with dementia have been more exposed to surgery and inhalational anaesthetics than individuals without dementia.METHODS: Using 457 cases from a dementi
Designers focus on fashion and appearance, whereas safety and protection engineers and physiologists emphasize functions in terms of developing functional and protective clothing. Phase change materials (PCMs) have been used in textiles and clothing to achieve cooling or warming function. The objective of this paper was to compare effectiveness of PCM cooling or warming determined by critical fact
Human epidermal growth factor receptor 2 (HER2) is overexpressed and/or amplified in 15-20% of all breast cancers, and is associated with an aggressive tumour type with impaired prognosis and a predictive marker for trastuzumab treatment. HER2 status can be determined by immunohistochemistry (IHC) at protein level and by fluorescence in situ hybridisation (FISH) analysing gene amplification, and i
The cholesterol-lowering effect of oats is well established, but the crucial properties eliciting this effect need to be further investigated to optimize the use of oats as functional foods. Furthermore, there are almost no reports investigating the effect of oats on atherosclerosis development. This thesis describes our work with finding suitable mouse models to study cholesterol-lowering and ant
Monoclonal anti-collagen type II antibody CIIC1 is an arthritogenic autoantibody, which induces arthritis in mice. We crystallized and solved the structure of CIIC1 Fab molecule. Analysis of structure revealed an interaction between the CDR regions of one Fab to the CH1 domain of another Fab, which resembles an antibody-antigen interaction. ELISA experiments confirmed the cross-reactivity of both
