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The natural moisturizing factor (NMF) is a mixture of small water-soluble compounds present in the upper layer of the skin, stratum corneum (SC). Soaking of SC in water leads to extraction of the NMF molecules, which may influence the SC molecular properties and lead to brittle and dry skin. In this study, we investigate how the molecular dynamics in SC lipid and protein components are affected by

Traditionstext om Seneca

When the famous bishop of Lund, Peder Winstrup, died in 1679 he was laid to rest in a family crypt in Lund Cathedral alongside his wife. Following a restoration of the Cathedral in the late 19th century, Peder Winstrup's coffin was moved to the crypt, as the family grave was dismantled. In 2012, a decision was made to move his remains to a different location presenting scientists with an opportuni

Highly crystalline K2GeF6 micropowders were prepared by co-precipitation in the hydrofluoric acid-water-alcohol solution and studied by means of the cathodoluminescence and time-resolved luminescence spectroscopy under synchrotron radiation excitation at 7 K. The nature of various intrinsic emissions was revealed. The luminescence band at 510 nm detected under excitation by photons with the energy

Background: Asthma is a heterogeneous inflammatory airway disease that continues to cause considerable morbidity across the world, with poor asthma control leading to hospitalizations. Objective: The present study investigated the risk of rehospitalization, mortality, and the management of patients with asthma who had been hospitalized because of an asthma exacerbation. Methods: National Swedish h

The demand for agricultural products is expected to increase as a result of population growth, changed diets and demands for bioenergy. At the same time, agricultural yields in many regions are expected to be negatively impacted by climate change. Here we show, how altered winter conditions in combination with an extreme weather event impact reproductive development and yield of oilseed rape (Bras

Background: The predictive effects of change patterns of sleep problems on mental health after a long-term disaster remain poorly known. We examined the change patterns of sleep problems after the Wenchuan earthquake, and tested whether specific sleep-related change patterns could predict mental health problems (posttraumatic stress disorder [PTSD], anxiety, and depression) in the 10 years after W

The Constrained Application Protocol (CoAP) is a standard communication protocol for resource-constrained devices in the Internet of Things (IoT). Many IoT deployments require proxies to support asynchronous communication between edge devices and the back-end. This allows (non-trusted) proxies to access sensitive parts of CoAP messages. Object Security for Constrained RESTful Environments (OSCORE)

Spike glycoprotein is essential for the reproduction of the SARS-CoV-2 virus, and its inhibition using already approved antiviral drugs may open new avenues for treatment of patients with the COVID-19 disease. Because of that we analyzed the inhibition of SARS-CoV-2 spike glycoprotein with FDA-approved antiviral drugs and their double and triple combinations. We used the VINI in silico model of ca

Plastic anisotropy may strongly affect the stress and strain response in metals subjected to multiaxial cyclic loading. This anisotropy evolves due to various microstructural features. We first use simple models to study how such features result in evolving plastic anisotropy. A subsequent analysis of existing distortional hardening models highlights the difference between stress- and strain-drive

Background: Phylogeny construction can help to reveal evolutionary relatedness among molecular sequences. The spike (S) gene of SARS-CoV-2 is the subject of an immune selective pressure which increases the variability in such region. This study aimed to identify mutations in the S gene among SARS-CoV-2 sequences collected in the Middle East and North Africa (MENA), focusing on the D614G mutation,

The occurrence of a series of thin but persistent early Cambrian (Cambrian Age 4) brachiopod shell concentrations extending along a transect of some 150 km in NE Greenland, indicates the ability of the group to form widespread, skeletal pavements very early in the history of the phylum, its gregarious behaviour and ability to harness available nutrients. These extensive shell pavements within the

Objective: The Attempted Suicide Short Intervention Program (ASSIP) was adapted for hospital delivery and to address substance use problems as well as evaluated for feasibility, acceptability, and therapist fidelity in a series of preparatory steps (n = 28) and in a pilot randomized controlled trial, RCT (n = 34). Method: In the RCT, patients with suicide attempts and substance use problem(s) with

Plastic extension of Ezkil by Ramon Lazkano. Brass sheets, wood sheet, mosquito net, speakers, amplifier + 3 microphones and a guitarist when “needed”.

To a large extent functional diversity in cells is achieved by the expansion of molecular complexity beyond that of the coding genome. Various processes create multiple distinct but related proteins per coding gene – so-called proteoforms – that expand the functional capacity of a cell. Evaluating proteoforms from classical bottom-up proteomics datasets, where peptides instead of intact proteoform

To systematically address non-technical engineering skills (NTES), six mandatory "Engineering Days" (Ing-dagar) were introduced in two bachelor programmes. The students were also allowed to perform voluntary activities leading to a Certification of Non-technical Engineering Competences, a certificate the students can attach to their CVs. To be certified, the student must have performed activities

This paper examines whether Sherlock Holmes’ “Science of Deduction and Analysis,” as reconstructed by Hintikka and Hintikka (in: Eco U, Sebeok TA (eds) The sign of three: Peirce, Dupin, Holmes, Indiana University Press, Bloomington, 1983), exemplifies a logic of discovery. While the Hintikkas claimed it does, their approach remained largely programmatic, and ultimately unsuccessful. Their reconstr