Popular Abstract in Swedish Autoimmuna sjukdomar är tillstånd där vårt immunförsvar angriper den egna kroppen. Det finns ett flertal sådana sjukdomar av vilka jag huvud-sakligen har intresserat mig för rheumatoid artrit (RA) och multipel skleros (MS). De behandlingar som finns för de drabbade är idag främst riktade mot ergonomi, smärtlindring och olika former av immunsupres-sion (tex TNFa antikropThe causes of autoimmune diseases are largely unknown today, but there is evidence supporting a substantial complex genetic influence on many of these diseases as well as environmental factors and chance. In this thesis I have tried to get one step closer to the genetic causes of two autoimmune diseases through their induced counterparts in mice, namely rheumatoid arthritis (RA) and multiple scler

Abstract is not available

This report presents the result of a research project conducted in 2012-2013 that aimed to adjust the existing modularity theories so that they could be used in packaging development. The study resulted in a model that can be incorporated into an existing packaging design process, thereby complementing this with aspects of modularity. The research project was conducted in close collaboration with

Popular Abstract in Swedish Grupp A streptokocker (Streptococcus pyogenes) är bakterier som orsakar många vanliga infektioner som halsfluss och svinkoppor (impetigo). De kan också orsaka allvarliga infektioner som under 1900-talet blev alltmer ovanliga. I slutet av 1980-talet började dock allvarliga streptokockinfektioner bli vanligare igen. Det är oklart varför det har skett en ökning av allvarliCell wall-attached proteins (CWPs) are important for the virulence of Gram-positive bacteria, but are also targets for the host immune system. CWPs have a conserved COOH-terminal region, responsible for cell wall-sorting. A pattern based on this conserved region was developed. The pattern identifies genes encoding CWPs, with high sensitivity and specificity, in whole genomes of Gram-positive bacte

Simultaneous OH- and formaldehyde planar-LIF measurements have been performed in an optical engine using two laser sources working on 283 and 355 nm, respectively. The measurements were performed in a light- duty diesel engine, using n-heptane as fuel, converted to single- cylinder operation and modified for optical access. It was also equipped with a direct-injection, common-rail system as well a

Popular Abstract in Swedish Att fortsätta leva på mitt sätt. Medelålders kvinnor och menopaus/klimakteriet. Varje år passerar cirka 65 000 svenska kvinnor sin menopaus. Menopaus är en medicinsk term och avser tidpunkten för en kvinnas sista menstruation. Tidpunkten för menopaus kan därför i regel endast avgöras i efterhand, vanligtvis först efter ett års uppehåll av de naturliga menstruationernaTo deepen the understanding of menopause and its role in women's lives is the general aim of this thesis. Between 1995 and 2003, all women in two Swedish primary health care districts received a postal questionnaire, when they were 45, 50, 55 or 60. A total of 1681 women (76%) responded. Twenty-four women were given research interviews. The effects of menopause on quality of life (QoL) and number