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Mechanisms involved in the islet adaptation to insulin resistance were examined in mice of the C57BL/6J strain challenged with a high-fat (58%) diet for 8 weeks. Basal hyperglycemia commenced after 1 week, whereas hyperinsulinemia evolved after 8 weeks. Glucose elimination after an intravenous glucose challenge (1 g/kg) was significantly delayed after 1, 4, and 8 weeks on the high-fat diet compare

Phosphorus-31 nuclear magnetic resonance (NMR) spectra (103.2 MHz) were obtained from rabbit portal vein, urinary bladder, and taenia coli smooth muscle. The muscles were mounted isometrically as strips in a horizontal probe and superfused with oxygenated medium at 23 degrees C. Under these conditions the preparations could remain in a stable metabolic state for at least 24 h. The resonances obser

Ray-tracing simulations of mistuned sagittal diffractive - refractive X-ray lenses (DRXL) are presented. In this article, firstly the characteristic aberrations for various types of crystal misalignments within one-crystal and four-crystal DRXLs are considered, and the sensitivity of such an optical system to the mutual misalignment of its components is discussed. The simulations reveal that a DRX

Artikeln diskuterar några möjliga feministiska förhållningssätt till de religionsfilosofiska positionerna realism och non-realism. Artikeln ifrågasätter därefter positionernas dualistiska förutsättningar avseende existens och sanning och ger ett konstruktivt språkfilosofiskt förslag till hur man kan förstå förhållandet mellan språk och verklighet, där det inte längre blir nödvändigt att åberopa re

Background: The expression of gene batteries, genomic units of functionally linked genes which are activated by similar sets of cis- and trans-acting regulators, has been proposed as a major determinant of cell specialization in metazoans. We developed a predictive procedure to screen the mouse and human genomes and transcriptomes for cases of gene-battery-like regulation. Results: In a screen tha

What did make Europe's development different from that of other parts of the world?

Annamirl and the Stove of Delight. With reference to "folk art" and "folk art" research in Europe.

In the fourth century B.C., Athenians were often accused of avoiding their civic obligations and of concealing their wealth.1 These attested cases show that economic behaviour in classical Athens could be affected by taxation. The purpose of the present study is to systematically explore the economic incentives resulting from the taxation of wealth. The first issue is the effects of the property t

We present a rate equation model for self-assembled quantum dot formation, or Stranski-Krastanow growth. The model includes a kinetically defined critical wetting layer thickness and a subsequent wetting layer decomposition. With these rate equations, total island densities can be calculated under varying deposition conditions, i.e., temperature and deposition rate.

The effects of parallel-type and serial-type pore nonuniformities on the effective diffusivity and the permeability of a porous material were evaluated, constant porosity and constant specific surface area being assumed. Two structural models were considered. In the first model, the porous structure was described as a bundle of cylindrical capillaries penetrating the whole thickness of the materia

This analysis of DNA-ploidy heterogeneity in advanced gastric carcinomas is consistent with the hypothesis of the emergence of a single aneuploid cell clone as a crucial mechanism in the progression from early gastric carcinoma to advanced gastric cancer. The prognostic value of DNA-ploidy in gastric cancers has been a matter of controversy. Tumour DNA-ploidy heterogeneity, the presence within the

A laboratory procedure is described for measuring methane potentials of organic solid waste. Triplicate reactors with 10 grams of volatile solids were incubated at 55 degreesC with 400 ml of inoculum from a thermophilic biogas plant and the methane production was followed over a 50-day period by regular measurements of methane on a gas chromatograph. The procedure involves blanks as well as cellul

Human immunodeficiency virus-2 (HIV-2) is less pathogenic than HIV-1, and the disease progression in HIV-2-infected individuals seems to be similar to that seen in HIV-1-infected long-term nonprogressors. Cell-mediated immune responses and the production of noncytotoxic CD8(+) T-cell antiviral factors (CAF) and beta-chemokines have been correlated to protection against HIV-1 and associated with as

An association between Helicobacter infection and autoimmune hepatitis (AIH) in children was investigated. The prevalence of antibodies to H. pylori did not differ between the AIH and the control group, (22% versus 14%), and antibodies to non-gastric Helicobacter were not detected in either group. H. pylori DNA was found in two AIH liver tissues, but Helicobacter was not cultured from any sample.

We present calculations of ground state and excitation energies for ethene between metal electrodes. The model determines the effects of the electrodes by incorporating a heterogeneous and structured solvation model with the quantum mechanical description of the molecular system. The effects of the electrodes are of electrostatic origin and an external bias can be applied enabling a close connecti

Ten days of urinary outlet obstruction in the rat induced a threefold increase in bladder weight. Active force of control and hypertrophic bladder muscle strips was measured at varying PO2 levels after high-K+, carbachol, or electrical field stimulation. Highest force output was obtained with carbachol. Force per muscle area was lower in the hypertrophic muscles. The basal rates of oxygen consumpt