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Rotational coherent anti-Stokes Raman spectroscopy (CARS) applied to thermometry in high-pressure hydrocarbon flames
Dual-broadband rotational coherent anti-Stokes Raman spectroscopy (DB-RCARS) has been investigated for thermometry under high-pressure and high-temperature conditions, in the product gas of fuel-lean hydrocarbon flames up to 1 MPa. Initial calibration measurements made in nitrogen, oxygen, and air, at pressures up to 1.55 MPa and temperatures up to 1800 K, showed good agreement between experimenta
First proton-proton collisions at the LHC as observed with the ALICE detector: measurement of the charged-particle pseudorapidity density at root s=900 GeV
On 23rd November 2009, during the early commissioning of the CERN Large Hadron Collider (LHC), two counter-rotating proton bunches were circulated for the first time concurrently in the machine, at the LHC injection energy of 450 GeV per beam. Although the proton intensity was very low, with only one pilot bunch per beam, and no systematic attempt was made to optimize the collision optics, all LHC
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Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer.
Popular Abstract in Swedish Varje år drabbas cirka 8000 svenska kvinnor av bröstcancer, och antalet nyinsjuknade ökar årligen med någon procent. I Sverige idag finns fler än 90 000 kvinnor som har avslutat eller är under behandling för sjukdomen. Med hjälp av nya återfallsförebyggande läkemedel har prognosen kraftigt förbättrats och 5-årsöverlevnaden är nästan 90 %. Den stora utmaningen i dagens bOne of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. This thesis describes studies on the effect of amplified in breast cancer 1 (AIB1), a coactiv
Endogenous migration programs and orientation in passerine birds
Uniform Bounds on the Relative Error in the Approximation of Upper Quantiles for Sums of Arbitrary Independent Random Variables
Fix any n≥1. Let X~1,…,X~n be independent random variables. For each 1≤j≤n, X~j is transformed in a canonical manner into a random variable Xj. The Xj inherit independence from the X~j. Let sy and s∗y denote the upper 1y th −−− quantile of Sn=∑nj=1Xj and S∗n=sup1≤k≤nSk, respectively. We construct a computable quantity Q−−y based on the marginal distributions of X1,…,Xn to produce upper and lower b
What limits the pedestrian? Exploring perceptions of walking in the built environment and in the context of every-day life
Walkability is often researched from the perspective of certain physical features in the built environment. However, for this paper, the point of departure was to also treat walking as a transport mode for reaching destinations and performing every-day activities. A conceptual model addressing both perceptions of the built environment and perceived limits due to every-day activities was used as a
Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae
Background: Xylose reductase (XR) and xylitol dehydrogenase (XDH) from Pichia stipitis are the two enzymes most commonly used in recombinant Saccharomyces cerevisiae strains engineered for xylose utilization. The availability of NAD+ for XDH is limited during anaerobic xylose fermentation because of the preference of XR for NADPH. This in turn results in xylitol formation and reduced ethanol yield
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Genomic Diversity and Admixture Differs for Stone-Age Scandinavian Foragers and Farmers
Prehistoric population structure associated with the transition to an agricultural lifestyle in Europe remains a contentious idea. Population-genomic data from 11 Scandinavian Stone Age human remains suggest that hunter-gatherers had lower genetic diversity than that of farmers. Despite their close geographical proximity, the genetic differentiation between the two Stone Age groups was greater tha
Determining universal processes related to best outcome in emergency abdominal surgery: a multicentre, international, prospective cohort study.
Emergency abdominal surgery outcomes represent an internationally important marker of healthcare quality and capacity. In this study, a novel approach to investigating global surgical outcomes is proposed, involving collaborative methodology using 'snapshot' clinical data collection over a 2-week period. The primary aim is to identify internationally relevant, modifiable surgical practices (in ter
Measurement of pion, kaon and proton production in proton-proton collisions at [Formula: see text] TeV.
The measurement of primary [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text] production at mid-rapidity ([Formula: see text] 0.5) in proton-proton collisions at [Formula: see text][Formula: see text] 7 TeV performed with a large ion collider experiment at the large hadron collider (LHC) is reported. Particle identification is performed using the specific ionisat
Endoplasmic reticulum function in dendrites and dendritic spines of hippocampal neurons
Popular Abstract in Swedish Till och med kroppens allra enklaste celler är så avancerade att vi inte förstår i detalj hur de fungerar eller hur de påverkar kroppen. Nervceller tillhör kroppens mer avancerade celler och vi får erkänna att all den kunskap vi har om dem är mindre än vad som finns att veta. Komplexiteten hos hjärnan är mångfalt större för nervcellerna kommunicerar blixtsnabbt med varaIn the hippocampus, dendritic spines are compartmentalized postsynaptic micro-domains in the excitatory synapse. Subsets of bigger and mushroom-shaped hippocampal dendritic spines contain tubules and cisterns of endoplasmic reticulum (ER) that are connected to the soma and dendrites of the neuron. These ER containing spines differ in their ability to retain ER. We hypothesized a functional couplin
Arbetsmarknad i förändring – En analys av regionala branschförändringar över tid och dess betydelse för framtida arbetsmiljöarbete
Is There Really Something Which Might Be Called a 'Self-Demonstrating Picture' : Even Within Scientific Imagery? Some Observations on a Double Illusion of Communication
I will propose some ideas about such pictures claiming to be self-demonstrating or selfillustrating, mostly using some classical anatomy illustrations. Based on these you may say that the anatomy seems to create a remarkable, realistic pictorial code, which casts together in one single, selfdemonstrating shape, an object of knowledge with the properties of the natural object itself. This is the pa
From Speed Profile Data to Analysis of Behaviour
Classification of speed profiles is necessary to allow interpretation of automatic speed measurements in terms of road user behaviour. Aggregation without considering variation in individual profile shapes easily leads to aggregation bias, while classification based on exogenous criteria runs the risk of loosing important information on behavioural (co-) variation. In this paper we test how three
Soil moisture variations affect short-term plant-microbial competition for ammonium, glycine, and glutamate.
We tested whether the presence of plant roots would impair the uptake of ammonium ([Formula: see text]), glycine, and glutamate by microorganisms in a deciduous forest soil exposed to constant or variable moisture in a short-term (24-h) experiment. The uptake of (15)NH4 and dual labeled amino acids by the grass Festuca gigantea L. and soil microorganisms was determined in planted and unplanted soi
Human native lipoprotein-induced de novo DNA methylation is associated with repression of inflammatory genes in THP-1 macrophages
Background: We previously showed that a VLDL-and LDL-rich mix of human native lipoproteins induces a set of repressive epigenetic marks, i. e. de novo DNA methylation, histone 4 hypoacetylation and histone 4 lysine 20 (H4K20) hypermethylation in THP-1 macrophages. Here, we: 1) ask what gene expression changes accompany these epigenetic responses; 2) test the involvement of candidate factors mediat
Flood analysis using generalized logistic models in partial duration series
Abstract in Undetermined As a generalization of the commonly assumed Poisson distribution (PD) used to estimate the annual number of peaks over threshold in partial duration series (PDS) model, the negative binomial (NB) distribution is proposed in this study. Instead of generalized pareto distribution (GPD) and exponential distribution (ED) models popularly applied to predict the probability of t