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A Paradigm Shift in the Management of Patients with Parkinson's Disease

Background: Technological evolution leads to the constant enhancement of monitoring systems and recording symptoms of diverse disorders. Summary: For Parkinson's disease, wearable devices empowered with machine learning analysis are the main modules for objective measurements. Software and hardware improvements have led to the development of reliable systems that can detect symptoms accurately and

Teuvoahtiana meridionalis, a new species from Patagonia and Antarctica

The new species Teuvoahtiana meridionalis is described from Antarctica and Southern South America. Even though the new species is morphologically and chemically variable, it is mo-lecularly monophyletic and located in the genus Teuvoahtiana in the subfamily Xanthorioideae. The genetic variation could not be correlated to the variation in any other characters that could support any further division

THz Spectroscopic Electron Paramagnetic Resonance of the Fe3+Defect in GaN

We present a recently developed method for electron paramagnetic resonance (EPR) measurements in the THz spectral range. The method is based on spectroscopic ellipsometry and thus requires no cavity, unlike conventional EPR. This permits us to scan the frequency parameters in addition to the magnetic field parameters. To showcase this, both frequency and magnetic field scans are performed on Fe-do

Diversity and relationships between Andean shrubland puna butterflies in the genus Punargentus (Lepidoptera: Nymphalidae: Satyrinae)

Two new species and two new subspecies of the satyrine butterfly genus Punargentus Heimlich, P. atusparia sp. n., P. heimlichi sp. n., P. blanchardi libertas ssp. n. and P. atusparia yupania ssp. n., are described from north-central Peru (Ancash, Huánuco and La Libertad). The affinities of the new taxa are evaluated based on molecular data obtained using target enrichment and COI barcoding. Punarg

Twenty years on from the introduction of the high risk strategy for stroke and cardiovascular disease prevention : a systematic scoping review

Background and purpose: Early this century, the high risk strategy of primary stroke and cardiovascular disease (CVD) prevention for individuals shifted away from identifying (and treating, as appropriate) all at-risk individuals towards identifying and treating individuals who exceed arbitrary thresholds of absolute CVD risk. The public health impact of this strategy is uncertain. Methods: In our

Reconsidering Elleström’s medium-centered communication model : a critical inquiry

Lars Elleström’s impact on intermedial studies is undoubtedly foundational, multifaceted and systematic. However, his medium-centered model of communication may be said to rephrase some arbitrary communication constants, such as the principle of transfer/transmission of cognitive import between source and target and through the media product. These kind of theoretical attachments imply that severaLars Elleström’s impact on intermedial studies is undoubtedly foundational, multifaceted and systematic. However, his medium-centered model of communication may be said to rephrase some arbitrary communication constants, such as the principle of transfer/transmission of cognitive import between source and target and through the media product. These kind of theoretical attachments imply that severa

Testing the Applicability of Quartz and Feldspar for Luminescence Dating of Pleistocene Alluvial Sediments in the Tatra Mountain Foothills, Slovakia

Luminescence dating is a widely used method in combination with sedimentological analysis for reconstructing the landscape development of the Quaternary period. In this study, quartz and K-feldspar measurements were used to evaluate the luminescence characteristics with the aim of dating the deposits. The sediments were sampled from an abandoned gravel pit in the Biely Váh valley and eight sites i

Red blood cell-derived arginase release in hemolytic uremic syndrome

BackgroundHemolysis is a cardinal feature of hemolytic uremic syndrome (HUS) and during hemolysis excess arginase 1 is released from red blood cells. Increased arginase activity leads to reduced L-arginine, as it is converted to urea and L-ornithine, and thereby reduced nitric oxide bioavailability, with secondary vascular injury. The objective of this study was to investigate arginase release in

Cognitive Control in Distracted Dinosaurs

Cognitive control is a skill used to control one’s own behaviour to reach a goal. We compared this skill across archosaurs by using the distraction task on American alligators, emus, chickens, and common ravens. We investigated whether the animals would still find a food reward hidden behind one of two identical opaque barriers after picking up a food distraction. Results show that all species can

Dietary index based on the Food Standards Agency nutrient profiling system and risk of Crohn's disease and ulcerative colitis

Background: Nutri-score is now widely available in food packages in Europe. Aim: To study the overall nutritional quality of the diet in relation to risks of Crohn's disease (CD) and ulcerative colitis (UC), in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: We collected dietary data at baseline from validated food frequency questionnaires. We used a dietar

Evaluating the 11-year solar cycle and short-Term 10Be deposition events with novel excess water samples from the East Greenland Ice-core Project (EGRIP)

10Be is produced by the interaction between galactic cosmic rays (GCRs) and solar energetic particles (SEPs) with the Earth's atmospheric constituents. The flux of GCRs is modulated by the varying strength of the magnetic fields of the Earth and the Sun. Measurement of 10Be concentrations from polar ice cores is thus a valuable tool to reconstruct the variations in the geomagnetic field and solar

Accurate prediction of protein assembly structure by combining AlphaFold and symmetrical docking

AlphaFold can predict the structures of monomeric and multimeric proteins with high accuracy but has a limit on the number of chains and residues it can fold. Here we show that a combination of AlphaFold and all-atom symmetric docking simulations enables highly accurate prediction of the structure of complex symmetrical assemblies. We present a method to predict the structure of complexes with cub

Cognitively defined Alzheimer's dementia subgroups have distinct atrophy patterns

INTRODUCTION: We sought to determine structural magnetic resonance imaging (MRI) characteristics across subgroups defined based on relative cognitive domain impairments using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and to compare cognitively defined to imaging-defined subgroups. METHODS: We used data from 584 people with Alzheimer's disease (AD) (461 amyloid positive, 123

Magmatism during late Ordovician-early Silurian accretion of the Caledonides of Arctic Scandinavia : the Halti-Guolasjavri area revisited

In the Scandinavian Caledonides, evidence of syn-collisional magmatism related to extensional basin development immediately prior to late Silurian Baltica-Laurentia collision was considered restricted to exotic terranes until late Silurian ages were obtained from the Halti Igneous Complex (HIC), hosted by a thrust sheet (Corrovarre Nappe, CN) of continental affinity. Various orogenic models for th