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This paper aims to contribute to the knowledge on innovation processes in low- and medium-low-tech industries. Today, industries characterised as high-tech are perceived to be central to economic development, as the research intensity shields them from competition from low-wage countries. This is less the case for low-tech industries, but their economic importance continues to be large, however. I

Azimuthally anisotropic distributions of D-0, D+, and D*+ mesons were studied in the central rapidity region (vertical bar y vertical bar < 0.8) in Pb-Pb collisions at a center-of-mass energy root(S)(NN) = 2.76 TeV per nucleon-nucleon collision, with the ALICE detector at the LHC. The second Fourier coefficient upsilon(2) (commonly denoted elliptic flow) was measured in the centrality class 30%-50

Aim: Experimental cerebral ischemia and organ culture of cerebral arteries induce an increased endothelin ET(B) receptor-mediated contraction. The aim of the present study was to examine if cytokines and growth factors, known to be activated in ischemia, can influence the expression and function of endothelin receptors after organ culture. Methods: Rat middle cerebral arteries were cultured for 24

Abstract in UndeterminedThis article presents the development to reliably seal copper canisters containing the Swedish nuclear waste, using friction stir welding. To avoid defects and welding tool fractures, it is important to control the welding temperature within a span of 790–910 degrees C. A cascade controller is used to efficiently suppress fast power input disturbances reducing their impact on the temperature. The

The discovery of microRNAs (miRNAs), which are ~22 nucleotide RNAs that inhibit protein synthesis in a sequence-specific manner and are present in a range of species, has born hope of new therapeutic strategies. miRNAs play important roles in development "Development" of what??and disease, but they remain poorly studied in uropathologies beyond cancer. Here, we discuss biologica

Abstract in UndeterminedDuring steady fixation, observers make small fixational saccades at a rate of around 1-2 per second. Presentation of a visual stimulus triggers a biphasic modulation in fixational saccade rate-an initial inhibition followed by a period of elevated rate and a subsequent return to baseline. Here we show that, during passive viewing, this rate signature is highly sensitive to

Diabetes mellitus is one of the most common comorbidities in palliative care. Yet, the optimal handling of diabetes mellitus in dying patients is debated. This review aims to discuss comprehensively the scientific basis as of today for diabetes mellitus management decisions in end-of-life (EOL) care.

This paper is about early roots of supersymmetry, as found in the literature from 1940s and early 1950s. There were models where the power of "partners" in alleviating divergences in quantum field theory was recognized. However, other currently known remarkable features of supersymmetry, such as its role in the extension of the Poincare group, were not known. There were, of course, no supersymmetr

Shallow groundwater in unconsolidated sediments represents a substantial water resource in the Chinese Loess Plateau. However, prior to development of the water supply for agriculture, annual and seasonal fluctuation of the recharge mechanism should be clarified. Since the region is arid, the effect of plant water uptake on groundwater fluctuation must also be assessed. A study was therefore under

JavaScript is a sequential programming language, and Thread-Level Speculation has been proposed to dynamically extract parallelism in order to take advantage of parallel hardware. In previous work, we have showed significant speed-ups with a simple on/off speculation heuristic. In this paper, we propose and evaluate three heuristics for dynamically adapt the speculation: a 2-bit heuristic, an expo

Objective The NORAM (Nonrenal Wegener's Granulomatosis Treated Alternatively with Methotrexate [MTX]) trial demonstrated that MTX can replace cyclophosphamide (CYC) as remission-inducing treatment for patients with newly diagnosed early systemic antineutrophil cytoplasmic antibodyassociated vasculitis. Duration of relapse-free survival was longer among CYC-treated patients than among MTX-treated p

Objective The objective of this article is to determine if maternal obesity is associated with an increased risk of Down syndrome in the offspring and whether the risk estimates for trisomy 21 based on combined screening is affected by maternal body mass index (BMI). Methods Study group I consisted of a nationwide cohort of 1 568 604 women giving birth; outcome was infants born with Down syndrome

The sperm chromatin structure assay (SCSA) parameter DNA fragmentation Index (DFI) is a valuable tool for prediction of fertility in vivo. Clinical data show that a DFI above 30% is associated with very low chance for achieving pregnancy by natural conception or by insemination. Already when DFI is above 20% the chance of natural pregnancy is reduced, this despite normal conventional semen paramet

A statistically significant association with uterine rupture during a trial of labour after caesarean delivery was found in at least two studies for the following variables: inter-delivery interval (higher risk with short interval), birth weight (higher risk if 4000 g or over), induction of labour (higher risk), oxytocin dose (higher risk with higher doses), and previous vaginal delivery (lower ri

This study investigated patterns and controls of the seasonal and inter-annual variations in energy fluxes (i.e., sensible heat, H, and latent heat, lambda E) and partitioning of the water budget (i.e., precipitation, P; evapotranspiration, ET; discharge, Q; and soil water storage, Delta S) over five years (2001-2005) in a boreal oligotrophic fen in northern Sweden based on continuous eddy covaria

In conventional presentations of continuum mechanics, the reference placement of a solid body is taken to be independent of the observer. Furthermore, the Euclidean spaces associated with different frames of reference are taken to be identical. In this paper these assumption are abandoned and different framings, as well as reference placements, will correspond to different Euclidean spaces. This r

Enterococcus faecium is an important pathogen that is resistant to many antibiotics and is able to form biofilms on implanted medical devices. In this study, the efficacy of rifampicin-containing antibiotic regimens against biofilms of E. faecium in vitro was investigated by determination of the minimum biofilm eradication concentration and by time-kill experiments of bacteria in biofilms formed o

Infantile malignant osteopetrosis (IMO) is caused by lack of functional osteoclasts leading to skeletal abnormalities, blindness due to compression of the optic nerves, bone marrow (BM) failure and early death. In most patients TCIRG1, a proton pump subunit essential for bone resorption, is mutated. Oc/oc mice represent a model for IMO due to a deletion in Tcirg1 and die around 4 weeks. To determi

Ecology Letters (2011) ABSTRACT: Partial migration, whereby only a fraction of the population migrates, is thought to be the most common type of migration in the animal kingdom, and can have important ecological and evolutionary consequences. Despite this, the factors that influence which individuals migrate and which remain resident are poorly understood. Recent work has shown that consistent ind