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Insulin and Immunity: when complement takes control

We are studying an unexpected role of complement – in the physiology and metabolism of pancreatic beta-cells. Surprisingly, this is related to intracellular functions of complement and therefore changes the way we perceive this “blood” system and will likely inspire discovery of many other intracellular effects of complement. We study the role of intracellular complement factor C3 and membrane bou

https://www.protein-chemistry.lu.se/projects/insulin-and-immunity-when-complement-takes-control - 2025-07-31

Bacterial complement evasion strategies

As a first line of defense against pathogens and a mediator between innate and adaptive immunity, complement is a particular focus of evasion strategies developed by pathogens.  We showed that one common strategy is to bind complement inhibitor C4BP, which leads to decreased opsonisation of bacteria with C3b impairing phagocytosis and allowing bacterial survival. It appears that binding of C4BP is

https://www.protein-chemistry.lu.se/projects/bacterial-complement-evasion-strategies - 2025-07-31

Pathologic complement activation in diseases

  Myriam Martin, Rebecca Trattner and Anna Blom Misguided or excessive complement activation is involved in many common diseases such as rheumatoid arthritis, systemic lupus erythematosus, vasculitis and age-related macula degeneration. In collaboration with clinicians we are studying molecular mechanisms of complement involvement in these diseases. Joint inflammation in rheumatoid arthritis (RA),

https://www.protein-chemistry.lu.se/projects/pathologic-complement-activation-diseases - 2025-07-31

Complement and cancer

Expression of COMP in breast cancer tissue Complement-dependent cytotoxicity is one of the mechanisms by which therapeutic monoclonal antibodies are toxic to cancer cells. Also, complement is currently undergoing re-appreciation of its role in the immune surveillance of tumors. The majority of human tumors are low immunogenic and complement may be involved in their recognition via direct “danger s

https://www.protein-chemistry.lu.se/projects/complement-and-cancer - 2025-07-31

Inherited deficiencies of complement inhibitors

Complement has recently gained substantial worldwide attention, as it was discovered that several common diseases such as age-related macular degeneration (blindness in elderly) are related to deregulation of the balance between complement activation and inhibition. Full complement deficiencies lead to severe infectious and autoimmune diseases but are uncommon while it appears that we are just beg

https://www.protein-chemistry.lu.se/projects/inherited-deficiencies-complement-inhibitors - 2025-07-31

Members of our research group

Myriam Martin, Rebecca Trattner and Anna Blom  You can reach us by mailor by calling 040-33 78 30 and 040-33 15 20Vaishnavi Dandavate, postdoctoral fellowE-mail: vaishnavi [dot] dandavate [at] med [dot] lu [dot] se (vaishnavi[dot]dandavate[at]med[dot]lu[dot]se)Daniel Chacón Arguedas, postdoctoral fellowE-mail: daniel [dot] chacon_arguedas [at] med [dot] lu [dot] seAlexander Ekström, PhD studentE-m

https://www.protein-chemistry.lu.se/members-our-research-group - 2025-07-31

Open positions

Here you can find description of open positions and internships in our research group. MSc StudentsWe often can offer thesis projects for Masters students within the projects conducted in our group. Please, contact Anna Blom (Anna [dot] Blom [at] med [dot] lu [dot] se (Anna[dot]Blom[at]med[dot]lu[dot]se)) directly for more details.PhD StudentsWe are always interested in reviewing PhD students appl

https://www.protein-chemistry.lu.se/open-positions - 2025-07-31

Research funding

Research funding supporting projects conducted in our research group: Swedish Research Council Cancerfonden Torsten Söderberg Foundation ALF Knut and Alice Wallenberg Foundation Novo nordisk fonden Erling-Persson Family Foundation Alfred Österlund Foundation  Grants for clinical research from Skåne University Hospital (including cancer) King Gustav Vth, 80-years Anniversary Foundation Diabetesfond

https://www.protein-chemistry.lu.se/research-funding - 2025-07-31

Anna Blom Research Group

The Medical Protein Chemistry research group headed by prof. Anna Blom is located at the Wallenberg Laboratory within Skåne University Hospital in Malmö. The group is focused on the complement system in health and disease. Our ambition is to make high quality basic science based on clinically relevant questions and yielding novel diagnostic approaches and clinical interventions. Our research is su

https://www.protein-chemistry.lu.se/anna-blom-research-group - 2025-07-31

start

Leading research in psychological defence About the institute... The Lund University Psychological Defence Research Institute (Forskningsinstitutet för psykologiskt försvar) is a multidisciplinary research unit within the Department of Communication. Our work focuses on the theory and practice of psychological defence, with a focus on research into analyzing and countering hostile information infl

https://www.psychologicaldefence.lu.se/start - 2025-07-31

About the institute

The Lund University Psychological Defence Research Institute (Forskningsinstitutet för psykologiskt försvar) is a multidisciplinary research unit within the Department of Communication. Our work focuses on the theory and practice of psychological defence and research into analyzing and countering hostile information influence operations and hybrid threats. The purpose of psychological defence is t

https://www.psychologicaldefence.lu.se/about-institute - 2025-07-31

ADAC.io

Attribution – Data – Analysis – Countermeasures. InterOperability ADAC.io is a Horizon project coordinated by the Psychological Defence Research Institute As of 1 February 2024, the Psychological Defence Research Institute coordinates the Horizon project ADAC.io, engaging seven partners in a three-year-long project. Based on the concept of Foreign Information Manipulation & Interference (FIMI) as

https://www.psychologicaldefence.lu.se/adacio - 2025-07-31

Research

Below are some of the main publications by the Psychological Defence Research Institute and our affiliates. 2025Pamment, J. & Tsurtsumia, D. (2025). Beyond Operation Doppelgänger: A Capability Assessment of the Social Design Agency. MPF Report Series, 8/2025, 1-194.Ördén, H. (2025). A genealogy of Swedish psychological defence: Information influence as a shifting problem for democratic governance.

https://www.psychologicaldefence.lu.se/research - 2025-07-31

Accessibility Statement

Accessibility of LURN - Lund Respiratory Network This website is run by the Lund Respiratory Network. We want as many people as possible to be able to use this website, and this document describes how lurn.lu.se complies with the accessibility regulations, any known accessibility issues, and how you can report problems so that we can fix them. How accessible is lurn.lu.se? We know some parts of th

https://www.lurn.lu.se/contact/accessibility-statement - 2025-07-31

The 21st LURN Conference

Save the Date: 12-13 March 2026Theme: “Early treatment potentials for lung disease”. Confirmed speakers (so far):Anders Blomberg, Professor and Senior Consultant in Internal and Respiratory Medicine, Head of Department of Public Health and Clinical Medicine, Umeå UniversityMagnus Sköld, Professor/Senior Physician, Idiopathic pulmonary fibrosis (IPF) -research group, Department of Medicine, Karolin

https://www.lurn.lu.se/lund-respiratory-network/21st-lurn-conference - 2025-07-31

Previous meetings

2025 | 20 years of translational lung research– challenges for the futureKeynote speakersSalman Siddiqui, Imperial College, London |“Precision Medicine In Asthma: Biomarkers And Phenotyping”Anna Smed Sörensen, Karolinska Institutet | “Immunological Mechanisms Of Sarcoidosis”Daniil Lisik, Gothenburg University | ““Using Ai To Characterize Trajectories Of Asthma And Allergy In Children”Tji-Joong Gan

https://www.lurn.lu.se/lund-respiratory-network/previous-meetings - 2025-07-31

Contact

Jonas Erjefält | Luftvägsinflammation jonas [dot] erjefalt [at] med [dot] lu [dot] se  Ellen Tufvesson | Lungmedicin och Allergologi ellen [dot] tufvesson [at] med [dot] lu [dot] se Lena Uller | Respiratorisk immunofarmakologi lena [dot] uller [at] med [dot] lu [dot] se Leif Bjermer | Lungmedicin och Allergologi leif [dot] bjermer [at] med [dot] lu [dot] se  Gunilla Westergren-Thorsson | Lungbiolo

https://www.lurn.lu.se/lund-respiratory-network/contact - 2025-07-31

Lund Respiratory Network

Lund Respiratory Network, LURN, was officially started in May 2003 and was constituted as an association in March 2010. It is an association established to facilitate collaborations in respiratory research. The aim is to connect and highlight research in the airway area and contribute to the exchange of knowledge and cooperation among colleagues in the country's southern healthcare region.LURN wor

https://www.lurn.lu.se/lund-respiratory-network - 2025-07-31