Local changes in cerebral energy metabolism due to brain retraction during routine neurosurgical procedures
Patients and Interventions. Tissue damage caused by brain retraction was evaluated utilizing intracerebral microdialysis in six patients operated on subfrontally for pituitary adenoma. The microdialysis probes (membrane length 10 mm, cut-off 20 kDalton) were placed in cerebral cortex beneath the brain retractor and perfused with Ringer solution at 0.3 mul/min. The microdialysis vials were changed
