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Radical radiotherapy for prostate cancer : patterns of care in Sweden 1998–2016

Introduction: Radiotherapy is an established treatment option for prostate cancer (PCa), both as primary treatment and secondary treatment after radical prostatectomy (RP). Since 1998, detailed data on radiotherapy delivered to Swedish men with PCa (e.g. treatment modalities, absorbed doses, fractionation) have been collated within PCa data Base Sweden (PCBaSe). This study reports patterns of radi

Clinical group supervision in an intensive care unit : A space for relief, and for sharing emotions and experiences of care

Much has been written about models, aims and the concept of clinical group supervisional, although few studies are empirical or focus on intensive care. • The aim of the study was to illuminate the process and describe, using qualitative content analysis, the content of conversations carried out during the course of clinical group supervision sessions among Registered Nurses (RN) and enrolled nurs

Cancer Risk for Fingolimod, Natalizumab, and Rituximab in Multiple Sclerosis Patients

Objective: Novel, highly effective disease-modifying therapies have revolutionized multiple sclerosis (MS) care. However, evidence from large comparative studies on important safety outcomes, such as cancer, is still lacking. Methods: In this nationwide register-based cohort study, we linked data from the Swedish MS register to the Swedish Cancer Register and other national health care and census

The role of advocacy in critical care nursing : a caring response to another

With the aim of clarifying critical care nursing, six critical care nurses, working in a Swedish intensive care unit (ICU) were each asked to narrate a care situation with which they had been satisfied or dissatisfied. The stories were tape-recorded and analysed using a phenomenological-hermeneutic approach inspired by the philosophy of Ricoeur. The themes uncovered in the analysis describe the nu

Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats

Maternal hypoglycaemia throughout gestation until gestation day (GD)20 delays foetal growth and skeletal development. While partially prevented by return to normoglycaemia after completed organogenesis (GD17), underlying mechanisms are not fully understood. Here, we investigated the pathogenesis of these changes and significance of maternal hypoglycaemia extending beyond organogenesis in non-diabe

Prescription of antibiotic agents in Swedish intensive care units is empiric and precise.

Since the prescription of antibiotics in the hospital setting is often empiric, particularly in the critically ill, and therefore fraught with potential error, we analysed the use of antibiotic agents in Swedish intensive care units (ICUs). We examined indications for antibiotic treatment, agents and dosage prescribed among 393 patients admitted to 23 ICUs at 7 tertiary care centres, 11 secondary

Populism and health inequality in high-income countries

The rise of populist parties and movements in general and right-wing populist parties in particular has been noted also in the public health literature. While economic and other factors behind the populist surge have been systematically analyzed in the political and social science literature, the understanding of this political phenomenon seems weak in important parts of the public health literatu

Shedding light on the governing mechanisms for insufficient CO and H2 burnout in the presence of potassium, chlorine and sulfur

Based on the experiences of insufficient burnout in industrial fluidized bed furnaces despite adequate mixing and availability of oxidizer, the influence of potassium on CO and H2 oxidation in combustion environments was investigated. The combustion environments were provided by a laminar flame burner in a range relevant to industrial furnaces, i.e. 845 °C to 1275 °C and excess air ratios ranging

Intermediation dilemmas in facilitated industrial symbiosis

Industrial symbiosis (IS) is a key paradigm for achieving circular economy among industrial firms. Achieving new IS projects often requires outside facilitation, and intermediaries can help solidify and expand existing IS networks. While various intermediary roles have been identified in the literature, less attention has been paid to the potential challenges that intermediaries might encounter in

Peptidoglycan in eukaryotes : Unanswered questions

Peptidoglycan has been retained in chloroplasts that have evolved from cyanobacteria along some evolutionary tracks, but has seemingly been quickly eliminated during evolution of others. It has been eliminated in Rhodophyta, Chlorophyta, Pteridophyta and Spermatophyta, but has been retained in streptophyte algae, Glaukophyta, and Lycophyta. In this article questions emerging from this are raised,

Closed-form H-infinity optimal control for a class of infinite-dimensional systems

H-infinity optimal control and estimation are addressed for a class of systems governed by partial differential equations with bounded input and output operators. Diffusion equations are an important example in this class. Explicit formulas for the optimal state feedback controller as well as the optimal state estimator are given. Unlike traditional methods for H-infinity synthesis, no iteration i

Optimisation based material parameter identification using full field displacement and temperature measurements

A material parameter identification is presented for a fully thermo-mechanically coupled material model based on full field displacement and temperature measurements. The basic theory of the inverse problem is recapitulated, focusing on the choice of the objective function, proposing a new formulation, and explaining in detail the necessary numerical treatment of experimental data during the pre-p

Accurate solution-adaptive finite difference schemes for coarse and fine grids

We introduce solution dependent finite difference stencils whose coefficients adapt to the current numerical solution by minimizing the truncation error in the least squares sense. The resulting scheme has the resolution capacity of dispersion relation preserving difference stencils in under-resolved domains, together with the high order convergence rate of conventional central difference methods

Nonlinear homogenization for topology optimization

Non-linear homogenization of hyperelastic materials is reviewed and adapted to topology optimization. The homogenization is based on the method of multiscale virtual power in which the unit cell is subjected to either macroscopic deformation gradients or equivalently to Bloch type displacement boundary conditions. A detailed discussion regarding domain symmetry of the unit cell and its effect on u

No-touch saphenous vein grafts in coronary artery surgery (SWEDEGRAFT) : Rationale and design of a multicenter, prospective, registry-based randomized clinical trial

The SWEDEGRAFT study (ClinicalTrials.gov Identifier: NCT03501303) tests the hypothesis that saphenous vein grafts (SVGs) harvested with the “no-touch” technique improves patency of coronary artery bypass grafts compared with the conventional open skeletonized technique. This article describes the rationale and design of the randomized trial and baseline characteristics of the population enrolled d

Towards eye tracking as a support tool for pilot training and assessment

A key challenge in pilot training and performance assessment is the lack of insight into pilot visual behavior. Without this, it is difficult for an instructor to assess, e.g., whether pilots fail because they did not monitor the instruments or because they did not act on them, and whether pilots comply with monitoring aspects of the Standard Operating Procedures. Eye tracking provides the opportu