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Pathogenic Autoreactive B Cells Are Not Negatively Selected toward Matrix Protein Collagen II.
We have addressed the importance of B cell tolerance to collagen type II, a matrix protein, which is a target in rheumatoid arthritis (RA) and its mouse models. We generated a germline-encoded anti-collagen type II (CII) IgH replacement anti-C1 B cell mouse strain (ACB) to investigate how B cell tolerance to CII, a matrix protein, is subverted and to further understand pathogenesis of RA. Phenotyp
Convergence of the T-matrix approach in scattering theory. II
Convergence of the T-matrix scheme is proved under more general assumptions than in Ramm [J. Math. Phys. 23, 1123–5 (1982)] and for more general boundary conditions. Stability of the numerical scheme towards small perturbations of data and convergence of the expansion coefficients are established. Dependence of the rate of convergence on the choice of basis functions is discussed. Dependence of th
Vibrotactile sense in patients with diabetes and carpal tunnel syndrome.
Aim: To evaluate vibration perception thresholds of patients with and without diabetes, before and after surgical carpal tunnel release. of patients with and without diabetes. Methods: In a prospective study, 35 consecutive patients with diabetes and carpal tunnel syndrome were age and gender matched with 31 patients without diabetes having idiopathic carpal tunnel syndrome. Preoperatively, 6, 12
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Localized proton magnetic resonance spectroscopy of cerebral abnormalities in children with carbohydrate-deficient glycoprotein syndrome
Two strands of rhetoric in advertising discourse
There are two interpretations of rhetoric that are backed by a long tradition: as the theory of argumentation and persuasion, which is how it was born in Antiquity, and as the taxonomy of rhetorical figures, which is the form in which it reigned supreme from the 16th century onwards. In both of these senses, advertising discourse today is the favoured, and in fact almost exclusive, domain of rheto
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Peter Weiss: The Aesthetics of Resistance, Volume 1: A Novel. Translated by Joakim Neugroschel. Foreword by Fredric Jameson.
Review of the English translation of the novel Die Ästhetik des Widerstands by German-Swedish writer Peter Weiss (1916 - 1982) in connection with the problems of the avant-garde as critical practice (the overall theme of this issue of the journal Reconstruction which is concluded by the review in question).
The reconfigured body. Human–animal relations in xenotransplantation.
The article explores issues concerning the reconfiguration of human and animal bodies in modern biotechnology. The examples are based on xenotransplantation: Transplantation of cells, tissue and organs from animals to humans. Three thematic issues that emerged from xenotransplantation research in Sweden in the 1990s and early 2000s are examined in the article. The first issue concerns how the pig
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Isotope shifts in dysprosium measured by high resolution laser spectroscopy
Using a pulsed dye laser, acting on a collimated atomic beam, the isotope shifts between the dysprosium isotopes 164, 162, and 160 were measured with high precision in three lines, , and 5652 Å.
Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.
Recent studies have suggested that regeneration of non-haematopoietic cell lineages can occur through heterotypic cell fusion with haematopoietic cells of the myeloid lineage. Here we show that lymphocytes also form heterotypic-fusion hybrids with cardiomyocytes, skeletal muscle, hepatocytes and Purkinje neurons. However, through lineage fate-mapping we demonstrate that such in vivo fusion of lymp
Socialdemokratins svarta pedagogik
Millbourn använder Alice Millers begrepp "den svarta pedagogiken" för att beskriva den pedagogiska tradition som den socialdemokartiska rörelsens elitskikt föll in i. Den svarta pedagogiken är auktoritär och skapar skuldkänslor hos barnet. Dess alternativ, en icke-auktoritär pedagogik som har en grundmurad tro på barnets egen förmåga, menar Millbourn kan beskriva arbetarnas självverksamheter såsom
Tystnad råder - Om tysk historiekultur
Fracture mechanics concepts applied to moment capacity and rotational capacity of reinforced concrete beams
The theoretical stress-strain relation in the compression zone of a concrete beam is determined by means of an approximate application of a model with strain softening and localization, i.e. with the descending branch described as a stress-deformation relation instead of a stress-strain relation. The results in a stress-strain relation for the compression zone, which is strongly dependent on the d
Life and Death in the City: Demography and Living Standards during Stockholm's Industrialization
This dissertation uses longitudinal micro-data from Stockholm between 1878 and 1926 to study the causes and consequences of the fertility transition and to examine the development of living standards inequality during industrialization. Although both processes have received much interest from researchers, we know relatively little of how either one played out among individuals in urban areas, whic