Flt3 has emerged as a potential regulator of hematopoietic stem cells (HSC). Sixty percent of cells in the mouse marrow Lin(-)Sca1(+)c-kit(+) HSC pool expressed flt3. Although single cell cloning showed comparable high proliferative, myeloid, B, and T cell potentials of Lin(-)Sca1(+)c-kit(+)flt3(+) and Lin(-)Sca1(+)c-kit(+)flt3(-) cells, only Lin(-)Sca1(+)c-kit(+)flt3(-) cells supported sustained

The influence of added colloidal particles on the phase separation of mixed aqueous polymer solutions is investigated. Two types of particles (polystyrene latex or silica) and different combinations of segregating polymers (dextran of varying molar mass combined with poly(ethylene oxide) (PEO) of varying molar mass, or Ucon, a copolymer of ethylene oxide and propylene oxide) were used. All systems

Pseudohyphae formation by Candida albicans blastoconidia, as seen in vaginal smears, is a phenotypical change commonly assumed to mean fungal invasiveness, i.e. not mere colonization. C. albicans forms germ tubes in vitro in the presence of serum. In our search for inhibitory components of germ tube formation, we decided to study fibrinogen. The inhibition of germ tube formation by clinical isolat

In this work we discuss a theory for entanglement generation, characterization and detection in fermionic two-particle interferometers (2PIs) at finite temperature. The motivation for our work is provided by the recent experiment by the Heiblum group (Neder et al 2007 Nature 448 333) realizing the two particle interferometer proposed by Samuelsson et al (2004 Phys. Rev. Lett. 92 026805). The exper

A new family of polymer conjugates is proposed to overcome constraints in the applicability of aqueous two-phase systems for the recovery of lactic acid. Polyethylene glycol-polyethylenimine (PEI) conjugates and ethylene oxide propylene oxide-PEI (EOPO-PEI) conjugates were synthesized. Aqueous two-phase systems were generated when the conjugates were mixed with fractionated dextran or crude hydrol

Local metabolic changes are suggested to be involved in muscle pain development in humans. Nineteen women with chronic work-related trapezius myalgia (TM) and 20 healthy female controls (CON) were studied during baseline rest, 20 min repetitive low-force exercise, and 120 min recovery. Interstitial serotonin (5-HT), glutamate, lactate, pyruvate, and blood flow were determined by microdialysis in t

Aims/hypothesis Recent genome-wide association studies performed in selected patients and control participants have provided strong support for several new type 2 diabetes susceptibility loci. To get a better estimation of the true risk conferred by these novel loci, we tested a completely unselected population of type 2 diabetes patients from a Norwegian health survey (the HUNT study). Methods We

Observations of the planetary nebula NGC3918 made with the STIS instrument on the Hubble Space Telescope reveal the first unambiguous detection of a hyperfine-induced transition 2s2p P-3(0)o-->2s(2) S-1(0) in the berylliumlike emission line spectrum of N IV at 1487.89 Angstrom. A nebular model allows us to confirm a transition rate of 4x10(-4) sec(-1)+/-33% for this line. The measurement represent

We examine the static and dynamic stability of the solutions of the Gross-Pitaevskii equation and demonstrate the intimate connection between them. All salient features related to dynamic stability are reflected systematically in static properties. We find, for example, the obvious result that static stability always implies dynamic stability and present a simple explanation of the fact that dynam

Recently, we showed that 10.2% of consecutively patch-tested hand eczema patients had a positive patch test to a selection of fragrances containing fragrances relevant to hand exposure. In this study, we used repeated skin exposure to a patch test-positive fragrance allergen in patients previously diagnosed with hand eczema to explore whether immersion of fingers in a solution with or without the

Closely related sympatric species are expected to evolve strong species discrimination because of the reinforcement of mate preferences [1-4]. Fitness costs of heterospecific matings are thought to be higher in females than in males, and females are therefore expected to show stronger species discrimination than males [5, 6]. Here, we investigated gender and species differences in sexual isolation

This study investigated the effect of two types of feedback (confirmatory and disconfirmatory) on the accuracy in witnesses' confidence judgements of their event memory. Overall, the witnesses evidenced overconfidence both when they received feedback and in the Control condition (no feedback). The results showed that confirmatory feedback caused higher overconfidence, compared both with when recei

The aim of this study was to investigate from the perspective of formal carers the care given to people aged 65 and over, who are cared for in their own homes by informal care. Thirty-three district nurses (DNs) and 20 home service assistants in a municipality with 13500 inhabitants (over 65 years old), were interviewed about the location of care recipients and 398 care recipients were located. Mo