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Genetic architecture of oral glucose-stimulated insulin release provides biological insights into type 2 diabetes aetiology

The genetics of β-cell function (BCF) offer valuable insights into the aetiology of type 2 diabetes (T2D)1,2. Previous studies have expanded the catalogue of BCF genetic associations through candidate gene studies3–7, large-scale genome-wide association studies (GWAS) of fasting BCF8,9 or functional islet studies on T2D risk variants10–14. Nonetheless, GWAS focused on BCF traits derived from oral

The effects of negation on discourse structure

In five sentence continuation studies we investigated how different forms of negation (negative quantifier, clausal negation, lexical negation) impact discourse structure in Swedish. We looked at what set of referents (the reference set for which some property holds, or the complement set, for which the property does not hold) speakers considered most noteworthy (speaker salient), and what form th

UNHCR Refugee Zakat Fund in Bangladesh : Sustainable religious funds for stateless refugees

This chapter analyzes the UNHCR Refugee Zakat Fund and the use of Islamic Social Welfare Instruments as a tool for supporting the refugee issue. Looking at the Refugee Zakat Fund from a legal and practical perspective, the research will try to understand the experience of this international non-Muslim organization in managing religious funds for Muslim refugees. The study will address the followin

Association Between Autoimmune Diseases and Monoclonal Gammopathy of Undetermined Significance : An Analysis From a Population-Based Screening Study

BACKGROUND: Monoclonal gammopathy of undetermined significance (MGUS) is a precursor of multiple myeloma (MM) and related conditions. In previous registry-based, retrospective studies, autoimmune diseases have been associated with MGUS. However, these studies were not based on a screened population and are therefore prone to ascertainment bias.OBJECTIVE: To examine whether MGUS is associated with

Development of a Multivariable Model to Predict the Need for Bone Marrow Sampling in Persons With Monoclonal Gammopathy of Undetermined Significance : A Cohort Study Nested in a Clinical Trial

BACKGROUND: Monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) are asymptomatic precursor conditions to multiple myeloma and related disorders. Smoldering multiple myeloma is distinguished from MGUS by 10% or greater bone marrow plasma cells (BMPC) on sampling, has a higher risk for progression, and requires specialist management.OBJECTIVE: To develop a

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INTRODUCTION: Impaired renal function as seen in chronic kidney disease (CKD) is a known risk factor for coronary artery diseases and has been linked to inferior outcome after myocardial revascularization. Studies on the outcome of coronary bypass grafting (CABG) in CKD-patients are scarce. We aimed to study this subgroup of patients following CABG in a well defined whole-nation cohort, focusing o

Män som vårdar : Manlighet och ambitioner om social förbättring i manlig diakoni i Sverige

Inledningsvis redogörs för Svenska Diakonsällskapets bakgrund och historiska rötter liksom för Diakonanstaltens initiering i Gävle. Bland annat ges som bakgrund en övergripande redogörelse för hur sociala förhållanden liksom den lutherska samhällssyn som dominerat det svenska enhetssamhället förändrades under 1800-talet. Dessa förändringar utgör en viktig kontext till förståelse av diakonins etabl

“Neither of the East nor of the West” : Crossing and Dwelling in Islamic Studies

What does it mean to do Islamic Studies within Religious Studies? Taking the cue from Thomas A. Tweed's intervention, this article discusses new theoretical and methodological approaches in Religious Studies and their relevance to researching Islam. Such approaches cross geographical, disciplinary, and intellectual boundaries while equally being emplaced in particular socio-cultural contexts that

A window to new opportunities? : Archival professionals in potential entrepreneur roles in the Swedish reality-TV show It's in the Walls

In this article we examine the present and future roles of archives and archivists in relation to contemporary institutional pressures to entrepreneurialise. We investigate them where they meet the public, where the information sector meets entertainment in a reading of the Swedish reality-TV show It’s in the Walls, where archives play a prominent role. We claim that the most likely archival entre

Sharpen existing tools or get a new toolbox? Contemporary cluster initiatives and regional transformation

This paper explores the evolving landscape of regional innovation policy, focusing on the interplay between traditional cluster policies and emerging transformative agendas. Over the past decade, policy initiatives aimed at fostering place-based, collaborative innovation have proliferated. However, questions arise regarding the adequacy of existing policy tools in accommodating newer, transformati